IP Library Granted Patent US 9,642,557
Granted Patent B2
US 9,642,557 · App. 13/926,840 · Granted May 9, 2017

Apparatus and method for breathing pattern determination using a non-contact microphone

Inventors: Benjamin Gavish (Mevaseret Zion, IL); Yoram Doron (Gedera, IL)
Assignee: 2BREATHE TECHNOLOGIES LTD.
A61B5/08A61B5/74A61B7/003A61B5/0816A61M15/00
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Quick Facts
Patent No.
US 9,642,557
App. No.
13/926,840
Granted
May 9, 2017
Kind
B2
Abstract

A method is provided for analyzing respiration of a subject ( 20 ). Using a non-contact microphone ( 22 ), a raw signal indicative of air-flow sounds of the respiration is generated. The raw signal is analyzed to determine a first set of one or more parameters of the respiration. An algorithm is applied to the first set of one or more parameters of the respiration. An algorithm is applied to the first set of parameters to derive a second set of one or more estimated parameters of the respiration that are not generally directly measurable in the raw signal. Other embodiments are also described.

Claims (29)

1. A method for analyzing respiration of a subject, the method comprising:

using a non-contact microphone, generating a raw signal indicative of airflow sounds of the respiration;

analyzing the raw signal to determine a first set of one or more parameters of the respiration;

applying an algorithm to the first set of parameters to derive a second set of one or more estimated parameters of the respiration; and

activating a sound synthesizer, a speaker and/or a visual display to provide a stimulus configured to guide the subject to perform breathing in a plurality of respiration phases determined at least in part responsively to the second set of parameters.

2. The method according to claim 1 , wherein applying the algorithm comprises setting the second set of one or more estimated parameters equal to a phenomenological function of the first set of one or more parameters.

3. The method according to claim 1 , wherein the first set of parameters includes a measure of breathing amplitude of the respiration, and wherein analyzing the raw signal comprises integrating the airflow sounds for a breath of the respiration to determine the measure of breathing amplitude.

4. The method according to claim 1 ,

wherein the first set of parameters includes a measure of breathing amplitude of the respiration,

wherein the second set of parameters is selected from the list consisting of: a measure of ventilation of the subject, and a measure of breathing irregularity of the subject, and

wherein applying the algorithm comprises applying the algorithm to the measure of breathing amplitude to derive the selected second set of parameters.

5. The method according to claim 1 , comprising analyzing at least one of the first and second sets of parameters to derive at least one additional breathing-related parameter of the subject selected from the list consisting of: breathing amplitude, a geometrical property of airflow of the subject, a characteristic of the airflow indicative of pursed lips breathing, a characteristic of the breathing indicative of relaxed breathing, a characteristic of the breathing indicative of passive elastic recoil of lungs of the subject, a characteristic of breathing with effort, and a characteristic of breathing during which the lungs of the subject undergo a functional change.

6. The method according to claim 1 , wherein guiding the subject to perform the breathing comprises treating insomnia of the subject by guiding the subject to perform the breathing in the plurality of respiration phases.

7. The method according to claim 1 , wherein the non-contact microphone includes a non-contact microphone of a consumer electronics device capable of performing at least one function that does not facilitate analyzing respiration of the subject, and wherein generating the raw signal comprises using the non-contact microphone.

8. The method according to claim 1 , wherein the non-contact microphone is integrated into a medical device in fluid communication with respiration-related airflow of the subject, and wherein generating the raw signal comprises using the integrated non-contact microphone.

9. The method according to claim 8 , wherein the medical device includes a drug inhaler, and wherein generating the raw signal comprises using the non-contact microphone integrated into the drug inhaler.

10. The method according to claim 1 , wherein analyzing the raw signal comprises deriving an expiratory airflow sound signal from the raw signal, and analyzing the expiratory airflow sound signal to determine the first set of parameters.

11. The method according to claim 10 , comprising generating a real-time indication for the subject that indicates whether expiration has been detected.

12. The method according to claim 10 , wherein the first set of parameters includes an active expiration time and a breathing period of the subject, and wherein analyzing the expiratory airflow sound signal comprises analyzing the expiratory airflow sound signal to determine the active expiration time and the breathing period.

13. The method according to claim 12 , wherein the second set of parameters includes an amplitude of a non-expiratory portion of the respiration, and wherein applying the algorithm comprises applying the algorithm to derive the amplitude of the non-expiratory portion of the respiration.

14. The method according to claim 12 , wherein the second set of parameters includes an inspiration time of the subject, and wherein applying the algorithm comprises applying the algorithm to derive the inspiration time.

15. The method according to claim 14 , wherein applying the algorithm to derive the inspiration time comprises:

determining whether a difference between the breathing period and the active expiration time is greater than or equal to a first function of the active expiration time;

responsively to a positive determination, setting the inspiration time equal to a second function of the difference; and

responsively to a negative determination, setting the inspiration time equal to a third function of the active expiration time.

16. The method according to claim 15 , wherein determining comprises determining whether the difference between the breathing period and the active expiration time is greater than or equal to the active expiration time.

17. The method according to claim 15 , wherein setting responsively to the positive determination comprises setting the inspiration time equal to a value within plus or minus 20% of the difference.

18. The method according to claim 17 , wherein setting responsively to the positive determination comprises setting the inspiration time equal to a value within plus or minus 10% of the difference.

19. The method according to claim 15 , wherein the second function includes a function of the difference and a phenomenological constant, and wherein setting responsively to the positive determination comprises setting the inspiration time equal to the second function of the difference and the phenomenological constant.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 6, 2016
From: INTERCURE LTD
To: YAZMONIT LTD.
Reel/Frame 039629/0419 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 6, 2016
From: YAZMONIT LTD.
To: 2BREATHE TECHNOLOGIES LTD.
Reel/Frame 039629/0582 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 20, 2013
From: GAVISH, BENJAMIN; DORON, YORAM
To: INTERCURE LTD.
Reel/Frame 031640/0263 →
Continuity (4)
Continuation 11958083 · Dec 17, 2007
Division 11572483
Provisional Application 60590508 · Jul 23, 2004
Related Publication 20130289431A1 · Oct 31, 2013