Dissolution of oxidized cellulose and particle preparation by dispersion and neutralization
View Patent ↗A process for dissolving modified cellulose includes contacting modified cellulose solution with at least one neutralizing agent to form a plurality of modified cellulose particles.
1. A process comprising:
contacting an oxidized cellulose with a solvent under an inert atmosphere to form a swelled oxidized cellulose;
adjusting the swelled oxidized cellulose to a first temperature;
contacting the swelled oxidized cellulose with a salt under the inert atmosphere to form an oxidized cellulose solution; and
adjusting the oxidized cellulose solution to a second temperature that is lower than the first temperature; and
contacting the oxidized cellulose solution with at least one neutralizing agent to form a plurality of oxidized cellulose particles.
2. The process according to claim 1 , wherein the at least one neutralizing agent is selected from the group consisting of ammonia, ammonium hydroxide, potassium hydroxide, sodium hydroxide, sodium carbonate, sodium bicarbonate, lithium hydroxide, potassium carbonate, potassium bicarbonate, and combinations thereof.
3. The process according to claim 1 , further comprising shearing the oxidized cellulose solution to form the plurality of oxidized cellulose particles.
4. The process according to claim 1 , wherein the first temperature is from about 115° C. to about 145° C. and the second temperature is from about 90° C. to about 120° C.
5. The process according to claim 1 , wherein the solvent is selected from the group consisting of N,N-Dimethylacetamide, N-methyl-2-pyrrolidinone, and combinations thereof.
6. The process according to claim 1 , wherein the salt is selected from the group consisting of lithium halides, sodium halides, potassium halides, and combinations thereof.
7. The process according to claim 1 , wherein the plurality of oxidized cellulose particles include oxidized cellulose having a degree of oxidation from about 80% to about 120% of a degree of oxidation of the predissolved oxidized cellulose.
8. The process according to claim 7 , wherein the plurality of oxidized cellulose particles have a molecular weight from about 80% to about 120% of the molecular weight of the predissolved oxidized cellulose.
9. A process comprising:
contacting an oxidized cellulose with a solvent under an inert atmosphere to form a swelled oxidized cellulose;
adjusting the swelled oxidized cellulose to a first temperature;
contacting the swelled oxidized cellulose with a salt under the inert atmosphere to form an oxidized cellulose solution; and
adjusting the oxidized cellulose solution to a second temperature that is lower than the first temperature; and
contacting the oxidized cellulose solution with at least one neutralizing agent to form a plurality of oxidized cellulose particles having a degree of oxidation from about 80% to about 120% of the degree of oxidation of the predissolved oxidized cellulose.
10. The process according to claim 9 , wherein the first temperature is from about 115° C. to about 145° C. and the second temperature is from about 90° C. to about 120° C.
11. The process according to claim 9 , further comprising shearing the dissolved oxidized solution to form the plurality of oxidized cellulose particles.
12. The process according to claim 9 , wherein the solvent is selected from the group consisting of N,N-Dimethylacetamide, N-methyl-2-pyrrolidinone, and combinations thereof.
13. The process according to claim 9 , wherein the salt is selected from the group consisting of lithium halides, sodium halides, potassium halides, and combinations thereof.
14. The process according to claim 9 , wherein the at least one neutralizing agent is selected from the group consisting of ammonia, ammonium hydroxide, potassium hydroxide, sodium hydroxide, sodium carbonate, sodium bicarbonate, lithium hydroxide, potassium carbonate, potassium bicarbonate, and combinations thereof.
15. A process comprising:
contacting an oxidized cellulose with a solvent under an inert atmosphere to form a swelled oxidized cellulose;
adjusting the swelled oxidized cellulose to a first temperature;
contacting the swelled oxidized cellulose with a salt under the inert atmosphere to form an oxidized cellulose solution; and
adjusting the oxidized cellulose solution to a second temperature that is lower than the first temperature; and
contacting the oxidized cellulose solution with at least one neutralizing agent to form a plurality of oxidized cellulose particles having a molecular weight from about 80% to about 100% of the molecular weight of the predissolved oxidized cellulose.
16. The process according to claim 15 , wherein the solvent is selected from the group consisting of N,N-Dimethylacetamide, N-methyl-2-pyrrolidinone, and combinations thereof.
17. The process according to claim 15 , wherein the salt is selected from the group consisting of lithium halides, sodium halides, potassium halides, and combinations thereof.
18. The process according to claim 15 , wherein the first temperature is from about 115° C. to about 145° C. and the second temperature is from about 90° C. to about 120° C.
19. The process according to claim 15 , further comprising shearing the oxidized cellulose solution to form the plurality of oxidized cellulose particles.
20. The process according to claim 15 , wherein the at least one neutralizing agent is selected from the group consisting of ammonia, ammonium hydroxide, potassium hydroxide, sodium hydroxide, sodium carbonate, sodium bicarbonate, lithium hydroxide, potassium carbonate, potassium bicarbonate, and combinations thereof.