Methods of Treating Recurring Bacterial Infection
The present invention relates to methods of treating a recurring gastrointestinal (GI) infection of Clostridium difficile in a subject comprising administering to the subject an effective amount of the compounds of the present invention.
1 . A method of treating a recurring gastrointestinal (GI) infection of Clostridium difficile in a subject comprising administering to the subject an effective amount of the compound of Formula I,
wherein the subject was previously treated for a GI infection of C. difficile.
2 . The method of claim 1 , wherein the compound of Formula I is administered as a pharmaceutical composition.
3 . The method of claim 2 , wherein the pharmaceutical composition of Formula I further comprises butylated hydroxy toluene.
4 . The method of claim 2 , wherein the pharmaceutical composition of Formula I is administered orally.
5 . The method of claim 1 , wherein the subject is a human.
6 . The method of claim 1 , wherein the subject was previously treated for the GI infection of C. difficile with a compound other than the compound of Formula I.
7 . The method of any of claim 1 , wherein the subject was previously treated for the GI infection of C. difficile with metronidazole.
8 . The method of claim 1 , wherein the subject was previously treated for the C. difficile infection with vancomycin.
9 . The method of claim 1 , wherein the subject was previously treated for the C. difficile infection with the compound of Formula I.
10 . The method of claim 1 , wherein the subject was previously treated more than once for a GI infection of C. difficile.
11 . The method of claim 2 wherein the pharmaceutical composition contains at least 93% of the compound of Formula I.
12 . The method of claim 11 wherein the pharmaceutical composition is administered as a tablet.
13 . The method of claim 11 wherein the pharmaceutical composition is administered as a capsule or suspension.