Catheter-based off-axis optical coherence tomography imaging system
A system for imaging a body lumen includes a controller and a display. The controller is configured to connect to a proximal end of a catheter having an optical fiber extending along the length of an elongate catheter body. The controller is further configured to rotate a distal end of the optical fiber from a location near a proximal end of the elongate catheter body, acquire optical coherence tomography (OCT) images using the optical fiber as the distal end of the optical fiber rotates, and determine a rotational lag of the distal end of the optical fiber. The display is configured to display one or more OCT images corrected for the rotational lag.
1. A system for imaging a body lumen, the system including:
a controller configured to connect to a proximal end of a catheter having a common path optical coherence tomography optical fiber extending off-axis along the length of an elongate catheter body relative to the catheter body, the controller configured to:
acquire a first optical coherence tomography (OCT) image by rotating a distal end of the common path optical coherence tomography optical fiber a single rotation in a first direction;
acquire a second OCT image by rotating the distal end of the common path optical coherence tomography optical fiber a single rotation in a second direction;
determine an angle of rotational difference between the first OCT image and the second OCT image;
acquire a plurality of OCT images of the body lumen as the distal end of the common path optical coherence tomography optical fiber rotates alternately a predetermined number of rotations in the first direction and a predetermined number of rotations in the second direction; and
rotationally adjust one or more of the plurality of OCT images of the body lumen by the angle of rotational difference after each change in direction that occurs during the alternating predetermined number of rotations; and
a display configured to display the one or more adjusted OCT images of the body lumen at a constant orientation relative to the body lumen even as the common path optical coherence tomography optical fiber rotates alternately in the first and second directions, the display further including an indicator configured to indicate which direction the distal end of the common path optical coherence tomography optical fiber is pointing around a perimeter of the catheter body.
2. The system of claim 1 , wherein the first and second predetermined number of rotations each comprise at least 360 degrees.
3. A system for imaging a body lumen, the system including:
a controller configured to connect to a proximal end of a catheter, the catheter including an elongate catheter body and an imaging sensor proximate to a distal end of the elongate catheter body, the controller configured to:
acquire a first optical coherence tomography (OCT) image by rotating a distal tip of the catheter and the imaging sensor relative to the elongate catheter body in a first direction;
acquire a second OCT image by rotating the distal tip of the catheter and the imaging sensor relative to the elongate catheter body in a second direction;
determine an angle of rotational difference between the first OCT image and the second OCT image;
acquire a plurality of OCT images of the body lumen as the distal tip of the catheter and the imaging sensor rotates alternately in the first direction and the second direction; and
rotationally adjust one or more of the plurality of OCT images by the angle of rotational difference after each change in direction; and
a display configured to display the one or more adjusted OCT images of the body lumen at a constant orientation relative to the body lumen even as the imaging sensor rotates alternately in the first and second directions.
4. The system of claim 3 , wherein the controller is further configured to store the angle of rotational difference for correction of additional OCT images.
5. The system of claim 3 , wherein the imaging sensor is an optical fiber extending off-axis at a distal end of the catheter.
6. The system of claim 3 , wherein acquiring a plurality of OCT images of the body lumen as the imaging sensor rotates alternately in the first direction and the second direction comprises acquiring the plurality of OCT images as the imaging sensor rotates alternately a predetermined number of rotations in the first direction and a predetermined number of rotations in the second direction.
7. The system of claim 6 , wherein the first and second predetermined number of rotations each comprise at least 360 degrees.
8. A system for imaging a body lumen, the system including:
a controller configured to connect to a proximal end of a catheter, the catheter having an elongate catheter body and an imaging sensor proximate to a distal end of the elongate catheter body, the controller configured to:
receive a first optical coherence tomography (OCT) image comprising a circumferential view of a lumen acquired by rotating the imaging sensor at least 360 degrees in a first direction, wherein rotating a distal end of the imaging sensor causes the imaging sensor to wind around a central lumen of the elongate catheter body in the first direction;
receive a second OCT image comprising a circumferential view of a lumen acquired by rotating the imaging sensor at least 360 degrees in a second direction, wherein rotating the distal end of the imaging sensor causes the imaging sensor to wind around the central lumen in the second direction;
determine a rotational lag of the imaging sensor based upon an angle of rotational difference required to align orientations of the first and second OCT images;
acquire a plurality of subsequent OCT images of the body lumen as the distal end of the imaging sensor rotates and the imaging sensor winds around the central lumen; and
rotationally correct one or more of the plurality of subsequent OCT images by the angle of rotational difference; and
a display configured to display the one or more of the plurality of subsequent OCT images of the body lumen corrected for the rotational lag, the display further including an indicator configured to indicate which direction the imaging sensor is pointing around a perimeter of the catheter body.
9. The system of claim 8 , wherein the display is configured to display the one or more of the plurality of subsequent OCT images at a substantially constant orientation.
10. The system of claim 8 , wherein the display is configured to indicate which rotational direction the imaging sensor is rotating.
11. The system of claim 8 , wherein the imaging sensor is an optical fiber extending off-axis at a distal end of the elongate catheter body.
12. The system of claim 8 , wherein the one or more of the plurality of subsequent OCT images are acquired as the distal end of the imaging sensor rotates alternately a predetermined number of rotations in the first direction and a predetermined number of rotations in the second direction.