Granted Patent B2

US 9,161,902 · App. 13/940,747 · Granted Oct 20, 2015

Abstract

Claims (11)

1. A method of treating acute urticaria or angioedema associated with an acute allergic reaction in an individual in need thereof, comprising

self-administering from an automatic injector a pre-measured dose of a composition comprising a non-sedating antihistamine either subcutaneously or intramuscularly,

wherein the automatic injector comprises a housing comprising a chamber for the non-sedating antihistamine composition and a dispensing assembly in communication with the chamber, and wherein the dispensing assembly provides for self-administration of the pre-measured dose of the non-sedating antihistamine composition subcutaneously or intramuscularly,

wherein the non-sedating antihistamine is cetirizine, levocetirizine, or a salt thereof.

2. The method of claim 1 , wherein the non-sedating antihistamine composition comprises a pH adjusting agent and has a pH of 3 to 9.

3. The method of claim 1 , wherein the non-sedating antihistamine is cetirizine or a salt thereof.

4. The method of claim 1 , wherein the non-sedating antihistamine composition further comprises ranitidine, cimetidine, epinephrine, methylprednisolone, prednisolone, or a combination thereof.

5. The method of claim 1 , further comprising self-administering from a second automatic injector an epinephrine composition, wherein the second automatic injector comprises a second housing comprising a second chamber for the epinephrine composition and a second dispensing assembly in communication with the second chamber.

6. The method of claim 1 , wherein treating is in an emergency situation.

7. The method of claim 1 , wherein self-administering the non-sedating antihistamine from the automatic injector is non-cardiotoxic and non-sedating.

8. The method of claim 1 , wherein the acute allergic reaction includes anaphylaxis.

Assignments (9)