Allantoin-containing skin cream
View Patent ↗An allantoin-containing skin cream composition can comprise allantoin and at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water. The composition is in the form of an oil-in-water emulsion. The pH of the composition is in a range of from about 3.0 to about 6.0; preferably, the pH of the composition is from about 5.0 to about 6.0. The composition can further comprise an acidic anionic polymer. A preferred acidic anionic polymer is a carboxypolymethylene polymer. The composition can further comprise a carbohydrate polymer such as galactoarabinan, polygalactose or polyarabinose. The composition can additionally comprise other ingredients such as herbal extracts, an antioxidant component, an emollient component, a chelator, a solvent component, or a preservative component. The composition is useful as a skin protectant.
1. A composition consisting essentially of an oil-in-water emulsion comprising:
(a) allantoin;
(b) an emulsifier system including beeswax and an anionic emulsifier that is substantially hydrophilic and is soluble in water; and
(c) an acid to adjust the pH of the composition to a pH of about 4.5 to about 5.8,
wherein the allantoin is stable in the composition for 30 days, 60 days, or 90 days at 40° C.
2. The composition of claim 1 , wherein the anionic emulsifier is selected from the group consisting of ammonium lauryl sulfate, sodium laureth sulfate, sodium oleyl succinate, ammonium lauryl sulfosuccinate, sodium dodecylbenzenesulfonate, ammonium laureth sulfate, sodium N-lauryl sarcosinate, sodium lauryl sulfate, and combinations thereof.
3. The composition of claim 2 , wherein the anionic emulsifier sodium lauryl sulfate.
4. The composition of claim 1 , wherein the acid comprises least one organic acid from 2 to 22 carbon atoms.
5. The composition of claim 4 , wherein the at least one organic acid is selected from the group consisting of citric acid, ascorbic acid, glycolic acid, lactic acid, benzoic acid, salicylic acid, and combinations thereof.
6. The composition of claim 1 , wherein the acid comprises least one inorganic acid.
7. The composition of claim 6 , wherein the at least one inorganic acid selected from the group consisting of hydrochloric acid, sulfuric acid, phosphoric acid, and combinations thereof.
8. The composition of claim 1 , wherein the acid comprises at least one organic acid and at least one inorganic acid.
9. The composition of claim 1 , wherein the allantoin is stable in the composition for 30 days at 40° C.
10. The composition of claim wherein the allantoin is stable in the composition for 1 days at 40° C.
11. The composition of claim 1 , wherein the allantoin is stable in the composition for 90 days at 40° C.
12. The composition of claim 1 , wherein the composition further comprises an emollient component.
13. The composition of claim 12 , wherein the emollient component comprises at least one emollient selected from the group consisting of lanolin oil, cetyl alcohol, stearyl alcohol, cod liver oil, butylated hydroxytoluene, and combinations thereof.
14. The composition of claim 1 , wherein the composition further comprises a preservative component.
15. The composition of claim 14 , wherein the preservative component comprises least one preservative selected from the group consisting of methylparaben, ethylparaben, propylparaben, butylparaben, phenoxyethanol, and combinations thereof.
16. The composition of claim 1 , wherein the composition further comprises a chelating agent.
17. The composition of claim 16 , wherein the chelating agent is tetrasodium EDTA.
18. The composition of claim 1 , wherein the composition further comprises a solvent component.
19. The composition of claim 18 , wherein the solvent component comprises at least one solvent selected from the group consisting of propylene glycol, glycerin, butylene glycol, and combinations thereof.
20. The composition of claim 1 , wherein the composition further comprises at least one component selected from the group consisting of fragrance, proteins, humectants, essential oils, vitamins, colorants, hydroxyacids, plant extracts, sunscreens, sodium hyaluronate, lipids, fatty acids, thickeners, panthenol, and combinations thereof.