Patent Application
App. No. 13/950,235
Injectable Nanoparticulate Olanzapine Formulations
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Abstract
Described are injectable formulations of particulate olanzapine that produce a prolonged duration of action upon administration, and methods of making and using such formulations. The injectable formulations comprise particulate olanzapine.
Claims (6)
1 . An injectable depot composition comprising:
(a) particles of olanzapine its salts, hydrates, solvates, polymorphs, co-crystalline, prodrugs, or analogues thereof, the particles having an effective average particle size of less than 5000 nm;
(b) at least one surface stabilizer adsorbed on the surface of the particles; and
(c) a pharmaceutically acceptable carrier,
wherein the injectable depot has a therapeutic efficacy of about one week or greater.
2 - 28 . (canceled)