Catheters with high-purity fluoropolymer additives
View Patent ↗The present invention provides catheter compositions that provide anti-thrombogenic properties while not adversely impacting mechanical properties. All embodiments of the present invention comprise a catheter that comprises a fluoropolymer additive with specific compositions and/or purity levels.
1. A catheter comprising:
an elongated tubular structure comprising a first polymer comprising polyurethane and a second polymer comprising polyfluoro-oligomeric groups;
wherein said second polymer is characterized by a polystyrene equivalent weight average molecular weight (M w ) greater than 13 kDa.
2. The catheter of claim 1 , wherein said second polymer has a polydispersity index of between 1.0 and 2.0.
3. The catheter of claim 2 , wherein said second polymer has a polydispersity index of between 1.0 and 1.5.
4. The catheter of claim 1 , wherein said second polymer is characterized by a polystyrene equivalent weight average molecular weight (M w ) within the range of 14 kDa to 26 kDa.
5. The catheter of claim 1 , wherein said polyurethane comprises a polycarbonate-based polyurethane.
6. The catheter of claim 1 , wherein said elongated tubular structure further comprises a radiopaque material.
7. The catheter of claim 6 , wherein said elongated tubular structure comprises about 25 weight percent to about 35 weight percent of said radiopaque material.
8. The catheter of claim 7 , wherein said elongated tubular structure comprises about 1.5 weight percent to about 2.5 weight percent of said second polymer.
9. The catheter of claim 6 , wherein said radiopaque material comprises barium sulfate.
10. The catheter of claim 9 , wherein said elongated tubular structure comprises up to about 30 weight percent of said barium sulfate.
11. The catheter of claim 1 , wherein said elongated tubular structure comprises an outer surface, at least one lumen, and a wall thickness between said outer surface and said at least one lumen, said wall thickness being at least 0.005 inches.
12. The catheter of claim 1 , wherein said elongated tubular structure comprises an outer surface, at least two lumens, and a wall thickness between said outer surface and any of said at least two lumens, said wall thickness being at least 0.005 inches.
13. The catheter of claim 1 , wherein said elongated tubular structure comprises an outer surface, at least three lumens, and a wall thickness between said outer surface and any of said at least three lumens, said wall thickness being at least 0.005 inches.
14. A catheter comprising:
an elongated tubular structure comprising a polymeric material comprising:
a first polymer comprising polyurethane; and
additives comprising a second polymer comprising polyfluoro-oligomeric groups;
wherein said second polymer is characterized by a polystyrene equivalent weight average molecular weight (M w ) greater than 13 kDa and a polydispersity index of between 1.0 and 2.0.
15. The catheter of claim 14 , wherein said polymeric material comprises up to about 44 weight percent of said additives.
16. The catheter of claim 14 , wherein said polymeric material comprises up to about 40 weight percent of said additives.
17. The catheter of claim 14 , wherein said polymeric material comprises up to about 33 weight percent of said additives.
18. The catheter of claim 14 , wherein said polymeric material comprises about 25 weight percent to about 35 weight percent of a radiopaque material.
19. The catheter of claim 18 , wherein said polymeric material comprises about 1.5 weight percent to about 2.5 weight percent of said second polymer.
20. The catheter of claim 19 , wherein said polymeric material comprises up to about 0.2 weight percent of a colorant.