IP Library Granted Patent US 8,747,906
Granted Patent B2
US 8,747,906 · App. 13/952,083 · Granted Jun 10, 2014

Dietary supplement enhancing the muscular energy metabolism, comprising an alkanoyl carnitine and ribose

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Quick Facts
Patent No.
US 8,747,906
App. No.
13/952,083
Granted
Jun 10, 2014
Kind
B2
Abstract

A method for treating myocardial or skeletal muscle anoxia which occurs in coronary or post-infarct disorders or during prolonged physical activity and muscle fatigue. This method comprises the administration of a combination composition comprising (a) an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine, propionyl L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof; and (b) ribose or a phosphate derivative thereof.

Claims (18)

1. A food/dietary supplement for the reduction of arrhythmia induced by myocardial anoxia, which comprises:

(a) an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine, and propionyl L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof; and

(b) ribose,

wherein the weight ratio of ingredients (a):(b) ranges from 1:1 to 1:10.

2. The supplement according to of claim 1 , further comprising: (c) a carnitine selected from the group consisting of L-carnitine, acetyl L-carnitine, butyryl L-carnitine and valeryl L-carnitine or the pharmacologically acceptable salts or mixtures thereof.

3. The supplement according to of claim 2 , wherein the weight ratio of ingredients (a):(b):(c) ranges from 1:1:1 to 1:10:2.

4. The supplement according to of claim 1 , which further comprises vitamins, sugars, coenzymes, mineral substances, ammo acids, peptides and antioxidants.

5. The supplement according to of claim 1 , wherein the pharmacologically acceptable salt is selected from the group consisting of: chloride; bromide; iodide; aspartate, acid aspartate; citrate, acid citrate; tartrate; phosphate, acid phosphate; fumarate, acid fumarate; glycerophosphate; glucose phosphate; lactate; maleate, acid maleate; mutate; orotate; oxalate; acid oxalate; sulphate, acid sulphate; trichloroacetate; trifluoroacetate and methane sulphonate.

6. A method for reducing arrhythmia induced by myocardial anoxia, comprising administering to an individual in need thereof the supplement according to claim 1 .

7. A method for reducing arrhythmia induced by myocardial anoxia, comprising administering to an individual in need thereof a combination composition consisting of:

(a) an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine, and propionyl L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof; and

(b) ribose,

wherein the weight ratio of ingredients (a):(b) ranges from 1:1 to 1:10.

8. The method of claim 7 , further comprising: (c) a carnitine selected from the group consisting L-carnitine, acetyl L-carnitine, butyryl L-carnitine and valeryl L-carnitine or the pharmacologically acceptable salts or mixtures thereof.

9. The method of claim 8 , wherein the weight ratio of ingredients (a):(b):(c) ranges from 1:1:1 to 1:10:2.

10. The method of claim 7 , wherein said combination compostion comprises vitamins, sugars, coenzymes, mineral substances, amino adds, peptides and antioxidants.

11. The method of claim 7 , wherein the pharmacologically acceptable salt is selected from the group consisting of: chloride; bromide; iodide; aspartate, acid aspartate; citrate, acid citrate; tartrate; phosphate, acid phosphate; fumarate, acid fumarate; glycerophosphate; glucose phosphate; lactate; maleate, acid maleate; mucate; orotate; oxalate; acid oxalate; sulphate, acid sulphate; trichloroacetate; trifluoroacetate and methane sulphonate.

12. The method of claim 7 , wherein the combination compostion is in the form of tablets, capsules, lozenges, pills, granules, creams, syrups or drops.