IP Library › Patent Application 13957886
Patent Application
App. No. 13/957,886

PREVENTION AND TREATMENT OF OCULAR SIDE EFFECTS WITH A CYCLOSPORIN

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Quick Facts
Patent No.
US None
App. No.
13/957,886
Abstract

Therapeutic methods are disclosed herein.

Claims (8)

1 .- 11 . (canceled)

12 . A method comprising:

administering a composition comprising cyclosporin A to a mammal before the mammal receives a therapeutically active agent,

wherein the therapeutically active agent is rituximab, and

wherein the method is effective in increasing tear production in a mammal whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca.

13 . The method of claim 12 , wherein the composition comprises cyclosporin A at a concentration of about 0.05%.

14 . The method of claim 13 , wherein the composition further comprises castor oil, polysorbate 80, and high molecular weight co-polymers of acrylic acid and a long chain alkyl methacrylate cross-linked with allyl ethers of pentaerythritol.

15 .- 19 . (canceled)

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2017
From: ALLERGAN, INC.
To: SAINT REGIS MOHAWK TRIBE
Reel/Frame 043830/0446 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 29, 2014
From: FEINERMAN, GREGG; BARTH, NEIL; SCHIFFMAN, RHETT; BARNETT, PAMELA S.
To: ALLERGAN, INC.
Reel/Frame 032082/0619 →