Method for the treatment or prevention of lower urinary tract symptoms
View Patent ↗This invention concerns a method for treatment or prevention of lower urinary tract symptoms with or without pelvic pain in an individual, said method comprising administering to the individual an effective amount of a selective estrogen receptor modulator, or an isomer, isomer mixture or a pharmaceutically acceptable salt thereof.
1. A method for treatment of obstructive lower urinary tract symptoms in a male individual, said method comprising administering to the individual an effective amount of (Z)-2-{2-[4-(4-Chloro-1,2-diphenylbut-1-enyl)phenoxy]ethoxy}ethanol (fispemifene), or an isomer, isomer mixture or a pharmaceutically acceptable salt thereof, wherein the obstructive lower urinary tract symptoms are caused by detrusor urethral sphincter dyssynergia.
2. The method according to claim 1 , wherein the detrusor urethral sphincter dyssynergia comprises bladder neck dyssynergia, external sphincter pseudodyssynergia, or Hinman syndrome.
3. The method according to claim 1 , wherein the obstructive lower urinary tract symptoms comprise hesitance, poor urinary stream, terminal dripping, or incomplete bladder emptying.
4. The method according to claim 2 , wherein the obstructive lower urinary tract symptoms comprise hesitance, poor urinary stream, terminal dripping, or incomplete bladder emptying.
5. The method according to claim 1 , wherein the method comprises administering to the individual an effective amount of fispemifene.
6. The method according to claim 2 , wherein the method comprises administering to the individual an effective amount of fispemifene.
7. The method according to claim 3 , wherein the method comprises administering to the individual an effective amount of fispemifene.
8. The method according to claim 4 , wherein the method comprises administering to the individual an effective amount of fispemifene.