Methods and water treatment systems for reducing bisphenol A release
View Patent ↗Disclosed are methods, compositions and systems pertaining to polymer coatings that entrap enzymes, specifically enzymes capable of reducing carboxylic acids.
1. A method of treating a composition comprising a bisphenol A (BPA) precursor, the method comprising:
contacting the composition comprising the BPA precursor with a carboxylic acid-reducing composition, wherein the carboxylic acid-reducing composition comprises a carboxylic acid-reducing enzyme and organic silane, and
wherein the BPA precursor comprises a polymer that produces BPA monomers upon polymer hydrolysis.
2. The method of claim 1 , wherein the BPA precursor comprises polycarbonate, polyester carbonate, or an epoxy resin.
3. The method of claim 1 , wherein the organic silane is formed from polymerization of methyltrimethoxysilane and gamma-aminopropyltriethoxysilane.
4. The method of claim 1 , wherein the carboxylic acid-reducing enzyme is entrapped in the organic silane.
5. The method of claim 1 , wherein at least one carboxylic acid-reducing enzyme is selected from carboxylate reductase, aldehyde ferredoxin oxidoreductase, formaldehyde ferredoxin oxidoreductase, glyceraldehyde-3-phosphate ferredoxin oxidoreductase, and (2R)-hydroxycarboxylate-viologen-oxidoreductase.
6. The method of claim 1 , wherein the carboxylic acid-reducing composition is in the form of a gel suspended in an adhesive film.
7. The method of claim 1 , wherein the carboxylic acid-reducing composition is contacted with at least a portion of the composition comprising the BPA precursor.
8. The method of claim 1 , wherein contacting comprises polymerizing the carboxylic acid-reducing composition directly onto at least a portion of the composition comprising the BPA precursor.
9. A method of treating water that contains 2,2-bis(4-hydroxyphenyl)propanoic acid (BPA-COOH), the method comprising:
contacting the water with (a) at least one carboxylic acid-reducing enzyme entrapped in a polymer, and (b) at least one carbonyl-reducing composition under conditions wherein the BPA-COOH is degraded.
10. The method of claim 9 , wherein at least one carboxylic acid-reducing enzyme comprises one or more of carboxylate reductase, aldehyde ferredoxin oxidoreductase, formaldehyde ferredoxin oxidoreductase, glyceraldehyde-3-phosphate ferredoxin oxidoreductase, and (2R)-hydroxycarboxylate-viologen-oxidoreductase.
11. The method of claim 9 , wherein the carbonyl-reducing composition is one or more of sodium borohydride, lithium aminoborohydride, and alcohol dehydrogenase.
12. The method of claim 9 , wherein the carboxylic acid-reducing enzyme and the carbonyl-reducing composition are contacted with the water sequentially.
13. The method of claim 9 , wherein the polymer is organic silane.
14. The method of claim 13 , wherein the organic silane is formed from polymerization of methyltrimethoxysilane and gamma-aminopropyltriethoxysilane.
15. A water treatment system that contains 2,2-bis(4-hydroxyphenyl)propanoic acid (BPA-COOH), comprising:
(a) an inlet to a treatment area, wherein the treatment area holds (i) a carboxylic acid-reducing composition comprising at least one carboxylic acid-reducing enzyme entrapped in polymerized organic silane, and (ii) at least one carbonyl-reducing composition; and
(b) an outlet from the treatment area.
16. The water treatment system of claim 15 , wherein the organic silane is formed from polymerization of methyltrimethoxysilane and gamma-aminopropyltriethoxysilane.
17. The water treatment system of claim 15 , wherein at least one carboxylic acid-reducing enzyme comprises one or more of carboxylate reductase, aldehyde ferredoxin oxidoreductase, formaldehyde ferredoxin oxidoreductase, glyceraldehyde-3-phosphate ferredoxin oxidoreductase, and (2R)-hydroxycarboxylate-viologen-oxidoreductase.
18. The water treatment system of claim 15 , wherein the at least one carbonyl-reducing compound is one or more of sodium borohydride, lithium aminoborohydride, and alcohol dehydrogenase.
19. The water treatment system of claim 15 , wherein the carboxylic acid-reducing composition is in the form of one or more of a non-perforated sheet, a perforated sheet, or beads.
20. The water treatment system of claim 15 , wherein the treatment area further comprises a first chamber that holds the carboxylic acid-reducing composition and a second chamber that holds the carbonyl-reducing composition.