IP Library Granted Patent US 10,118,149
Granted Patent B2
US 10,118,149 · App. 13/979,719 · Granted Nov 6, 2018

Oscillating flow minireactor

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Quick Facts
Patent No.
US 10,118,149
App. No.
13/979,719
Granted
Nov 6, 2018
Kind
B2
Abstract

The present invention relates to an apparatus comprising a) an unbaffled reactor or microreactor having a channel defined by a pathway, and b) an oscillating flow device, wherein the channel pathway comprises a plurality of directional changes. The reactor channel has a hydrolic diameter from 0.1 mm to 10 mm. A method of making said apparatus and the use of said apparatus to carry out a process on a suspension is also disclosed.

Claims (14)

1. An apparatus suitable for carrying out a process on a fluid, said apparatus comprising a) an unbaffled minireactor having a reactor channel defined by a pathway, and b) an oscillating flow device; wherein the reactor channel pathway comprises one or more directional changes; and wherein the net flow of the reaction stream is in the forward direction but the oscillating flow device slows, pauses and/or reverses this forward flow periodically; and wherein the frequency of the flow oscillation may vary from 0.1 Hz to 1000 Hz and the ratio between stationary flow to amplitude of oscillating flow may vary from 0.05 to 1000.

2. An apparatus according to claim 1 , wherein the reactor channel has a hydraulic diameter of from 0.01 mm to 10 mm.

3. An apparatus according to claim 1 , wherein the reactor channel has a constant hydraulic diameter.

4. An apparatus according to claim 1 , wherein each directional change has a ratio of hydraulic diameter, d h , to radius of curve, R c , of from 0.5 to 5.

5. An apparatus according to claim 1 , wherein each directional change has an angle of curve, a, of from 40° to 120°.

6. An apparatus according to claim 1 , wherein the ratio of the number of directional changes, N, to the length of the reactor channel pathway, L, is from 0.03/d h to 1/d h , where d h is the hydraulic diameter of the reactor channel pathway.

7. An apparatus according to claim 1 , wherein the reactor channel has a constant cross-section.

8. An apparatus according to claim 1 in which the reactor channel pathway is two dimensional.

9. An apparatus according to claim 1 , wherein the minireactor comprises a laminate structure.

10. An apparatus according to claim 1 , wherein the oscillating flow device is connected to the reactor channel and to at least one coolant channel within the minireactor.

11. A method of making an apparatus as defined in claim 1 comprising:

i) forming a channel in a sheet of material;

ii) stacking one or more of said sheets with one or more different sheets of material to form a laminated minireactor; and

iii) connecting said device to an oscillating flow device.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 1, 2018
From: PATHEON HOLDINGS I B.V.
To: PATHEON AUSTRIA GMBH & CO KG
Reel/Frame 047018/0142 →
CHANGE OF NAME Recorded Jun 8, 2018
From: DPX HOLDINGS B.V.
To: PATHEON HOLDINGS I B.V.
Reel/Frame 046328/0157 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 1, 2014
From: DSM IP ASSETS B.V.
To: JLL/DELTA DUTCH NEWCO B.V.
Reel/Frame 034282/0574 →
CHANGE OF NAME Recorded Dec 1, 2014
From: JLL/DELTA DUTCH NEWCO B.V.
To: DPX HOLDINGS B.V.
Reel/Frame 034500/0795 →
CHANGE OF ADDRESS Recorded Dec 1, 2014
From: DPX HOLDINGS B.V.
To: DPX HOLDINGS B.V.
Reel/Frame 034500/0851 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 2, 2013
From: REINTJENS, RAFAEL WILHELMUS ELISABETH GHISLAIN; THATHAGAR, MEHUL
To: DSM IP ASSETS B.V.
Reel/Frame 031701/0165 →
Cited By (1)
US 12,352,625