IP Library Granted Patent US 9,364,826
Granted Patent B2
US 9,364,826 · App. 13/982,666 · Granted Jun 14, 2016

Test chip and test chip unit incorporated with test chip

Inventor: Shigeru Wada (Kishiwada, JP)
Assignee: KONICA MINOLTA, INC
B01L3/021B01L3/502715G01N21/05G01N21/648G01N33/48707G01N35/1079B01L3/0275B01L2200/027B01L2200/0689B01L2300/044B01L2300/0636B01L2300/0877B01L2400/0487G01N2021/058G01N2035/00158
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Quick Facts
Patent No.
US 9,364,826
App. No.
13/982,666
Granted
Jun 14, 2016
Kind
B2
Abstract

The present invention discloses an arrangement provided with a chip body having a fluid channel and configured such that an end portion of the fluid channel is opened in a surface of the chip body, and a sheet-like seal member which covers at least the opening in the surface of the chip body for bringing the inside of the fluid channel to a sealed state. The seal member is constituted of laminated sheet members including a first sheet member having a ductility and an elasticity capable of forming a hole therein with use of a nozzle member, and a second sheet member having a lower ductility than the first sheet member. The sheet members adjoining each other are adhered to each other by an adhesive or a tackifier. The second sheet member is disposed on the chip body side than the first sheet member.

Claims (45)

1. A test chip unit comprising a test chip for use in performing a biochemical test by injecting and sucking a test solution with use of a pipette chip, wherein:

the test chip comprises:

a chip body including a fluid channel having a plurality of end portions, each of the end portions of the fluid channel opened in a surface of the chip body; and

a sheet-like seal member configured to cover at least the openings in the surface of the chip body for bringing an inside of the fluid channel to a sealed state, wherein

the pipette chip is structured to inject and suck the test solution in and out of the fluid channel;

the seal member comprises a plurality of laminated sheet members including a first sheet member having a predetermined ductility and a predetermined elasticity capable of forming a hole therein by pressing a tip of the pipette chip against the seal member, and a second sheet member having a lower ductility than the first sheet member, the sheet members adjoining each other being adhered to each other in a direction of laminating the sheet members,

the second sheet member is disposed on an inner side than the first sheet member in the sheet laminating direction, the inner side corresponding to a side of the chip body,

the pipette chip has a tip portion in a nozzle-like shape configured such that the tip of the pipette chip is opened, the pipette chip being formed into such a shape that a tip surface of the pipette chip surrounding a periphery of the opening is aligned in parallel or substantially aligned in parallel to the seal member when the tip of the pipette chip is pressed against the seal member of the test chip, and

the seal member is structured to have a tubular portion along the outer circumferential surface of the tip portion of the pipette chip when the hole is formed in the seal member with use of the tip portion of the pipette chip.

2. The test chip unit according to claim 1 , wherein

the seal member is configured such that the first sheet member is disposed on an outermost side among the sheet members.

3. The test chip unit according to claim 1 , wherein

the first sheet member has a total elongation of not smaller than 200% but not larger than 720%, and

the second sheet member has a total elongation of not larger than 50%.

4. The test chip unit according to claim 1 , wherein

the second sheet member is made of aluminum.

5. The test chip unit according to claim 1 , wherein

the seal member includes a third sheet member having a predetermined adhesive force, and

the third sheet member is disposed at a position closest to the chip body side in the sheet laminating direction.

6. The test chip unit according to claim 1 , wherein

an inner diameter of a portion of the fluid channel between the end portions is smaller than an inner diameter of the end portion.

7. The test chip unit according to claim 2 , wherein

the first sheet member has a total elongation of not smaller than 200% but not larger than 720%, and

the second sheet member has a total elongation of not larger than 50%.

8. The test chip unit according to claim 2 , wherein

the second sheet member is made of aluminum.

9. The test chip unit according to claim 3 , wherein

the second sheet member is made of aluminum.

10. The test chip unit according to claim 2 , wherein

the seal member includes a third sheet member having a predetermined adhesive force, and

the third sheet member is disposed at a position closest to the chip body side in the sheet laminating direction.

11. The test chip unit according to claim 3 , wherein

the seal member includes a third sheet member having a predetermined adhesive force, and

the third sheet member is disposed at a position closest to the chip body side in the sheet laminating direction.

12. The test chip unit according to claim 4 , wherein

the seal member includes a third sheet member having a predetermined adhesive force, and

the third sheet member is disposed at a position closest to the chip body side in the sheet laminating direction.

13. The test chip unit according to claim 2 , wherein

an inner diameter of a portion of the fluid channel between the end portions is smaller than an inner diameter of the end portion.

14. The test chip unit according to claim 3 , wherein

an inner diameter of a portion of the fluid channel between the end portions is smaller than an inner diameter of the end portion.

15. The test chip unit according to claim 4 , wherein

an inner diameter of a portion of the fluid channel between the end portions is smaller than an inner diameter of the end portion.

16. The test chip unit according to claim 5 , wherein

an inner diameter of a portion of the fluid channel between the end portions is smaller than an inner diameter of the end portion.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 21, 2022
From: KONICA MINOLTA, INC.
To: OTSUKA PHARMACEUTICAL CO., LTD.
Reel/Frame 059747/0589 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 30, 2013
From: WADA, SHIGERU
To: KONICA MINOLTA, INC.
Reel/Frame 030907/0391 →
Priority Claims (1)
JP 2011-018303 · Jan 31, 2011 · national
Continuity (1)
Related Publication 20130312546A1 · Nov 28, 2013