IP Library › Granted Patent US 9,943,605
Granted Patent B2
US 9,943,605 · App. 13/995,301 · Granted Apr 17, 2018

Polymer-semaxanib moiety conjugates

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Quick Facts
Patent No.
US 9,943,605
App. No.
13/995,301
Granted
Apr 17, 2018
Kind
B2
Abstract

The invention relates to (among other things) polymer-semaxanib moiety conjugates and related compounds. A compound of the invention, when administered by any of a number of administration routes, exhibits advantages over the semaxanib moiety in unconjugated form.

Claims (12)

1. A compound encompassed by the formula:

and pharmaceutically acceptable salts thereof, wherein n is from 3 to 10.

2. A composition comprising a compound of claim 1 and a pharmaceutically acceptable excipient.

3. A composition of matter comprising a compound of claim 1 , wherein the compound is present in a dosage form.

4. The compound of claim 1 , wherein n is from 3 to 9.

5. The compound of claim 1 , wherein n is 3.

6. The compound of claim 1 , wherein n is 4.

7. The compound of claim 1 , wherein n is 5.

8. The compound of claim 1 , wherein n is 6.

9. The compound of claim 1 , wherein n is 7.

10. The compound of claim 1 , wherein n is 8.

11. The compound of claim 1 , wherein n is 9.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded Apr 17, 2020
From: TC LENDING, LLC, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 053180/0009 →
RELEASE OF SECURITY INTEREST RECORDED AT REEL 31217, FRAME 0776 Recorded Oct 14, 2015
From: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 036876/0130 →
GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Oct 6, 2015
From: NEKTAR THERAPEUTICS
To: TC LENDING, LLC, AS COLLATERAL AGENT
Reel/Frame 036796/0562 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 4, 2013
From: RIGGS-SAUTHIER, JENNIFER; ALLUMS-DONALD, STEPHANIE; CULBERTSON, SEAN M.
To: NEKTAR THERAPEUTICS
Reel/Frame 031350/0543 →
SECURITY AGREEMENT Recorded Sep 16, 2013
From: NEKTAR THERAPEUTICS
To: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 031217/0776 →