Granted Patent
B2
US 9,827,326 · App. 13/996,834 · Granted Nov 28, 2017
Polymer-sunitinib conjugates
View Patent ↗
Loading inventors, assignments & file history…
Abstract
The invention relates to (among other things) polymer-sunitinib conjugates and related compounds. A compound of the invention, when administered by any of a number of administration routes, exhibits advantages over sunitinib in unconjugated form.
Claims (5)
1. A compound encompassed within the formula
and pharmaceutically acceptable salts thereof, wherein each n is an integer from about 100 to about 2270.
2. A composition comprising (i) a compound, of claim 1 , and (ii) a pharmaceutically acceptable excipient.
3. The compound of claim 1 , wherein each n is an integer from about 136 to about 2050.
4. The compound of claim 3 , wherein each n is an integer from about 225 to about 1930.
Assignments (5)
RELEASE OF SECURITY INTEREST
Recorded Apr 17, 2020
From: TC LENDING, LLC, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 053180/0009 →
RELEASE OF SECURITY INTEREST RECORDED AT REEL 31217, FRAME 0776
Recorded Oct 14, 2015
From: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 036876/0130 →
GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS
Recorded Oct 6, 2015
From: NEKTAR THERAPEUTICS
To: TC LENDING, LLC, AS COLLATERAL AGENT
Reel/Frame 036796/0562 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Oct 1, 2013
From: CULBERTSON, SEAN M.; KOZLOWSKI, ANTONI; VINSON, TONY DREW
To: NEKTAR THERAPEUTICS
Reel/Frame 031317/0618 →
SECURITY AGREEMENT
Recorded Sep 16, 2013
From: NEKTAR THERAPEUTICS
To: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 031217/0776 →