IP Library › Granted Patent US 9,388,276
Granted Patent B2
US 9,388,276 · App. 14/000,869 · Granted Jul 12, 2016

Monomers and polymers for functional polycarbonates and poly(ester-carbonates) and PEG-co-polycarbonate hydrogels

Inventors: Jie Song (Shrewsbury, MA); Jianwen Xu (Worcester, MA)
Assignee: University of Massachusetts
C08G64/0208A61L27/18C07C247/10C07D319/06C07D405/06C07D405/14C08G64/0241C08G64/0291C08G64/18C08G64/183
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Quick Facts
Patent No.
US 9,388,276
App. No.
14/000,869
Granted
Jul 12, 2016
Kind
B2
Abstract

The invention generally relates to functional polymers and hydrogels. More particularly, the invention provides versatile monomers and polymers with well-defined functionalities, e.g., polycarbonates and poly(ester-carbonates), compositions thereof, and methods for making and using the same. The invention also provides cytocompatible poly(ethylene glycol)-co-polycarobonate hydrogels (e.g., crosslinked by copper-free, strain-promoted “click” chemistry).

Claims (3)

1. A compound having the structural formula of:

wherein each of R 1 , R 2 , R 5 and R 6 is H; and each of R 3 and R 4 is —(CH 2 ) p —N 3 , wherein p is an integer from about 1 to about 16.

2. The compound of claim 1 , wherein p=1.

Assignments (1)
CONFIRMATORY LICENSE Recorded Dec 12, 2013
From: UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 031804/0380 →
Continuity (3)
Provisional Application 61446997 · Feb 25, 2011
Provisional Application 61484138 · May 9, 2011
Related Publication 20140058058A1 · Feb 27, 2014