Bioabsorbable polymers
Described herein are biocompatible compositions that contain a copolymer and a filler material. In particular, described herein are compositions that include a copolymer and a filler which may be a calcium salt. Also described herein are methods in which the compositions are used to attach soft tissue to bone.
1. A bioabsorbable polymer composition consisting of:
(a) from 65 to 70 percent by weight of a copolymer, based on the weight of said bioabsorbable polymer composition, wherein said copolymer is selected from the group consisting of poly l-lactide:co-glycolide, poly l-lactide:d,l-lactide, and mixtures thereof; and
(b) from 30 to 35 percent by weight of a ceramic filler, based on the weight of the bioabsorbable polymer composition, wherein said ceramic filler consists of calcium sulphate and optionally tricalcium phosphate.
2. The bioabsorbable polymer composition according to claim 1 , wherein the ratio of poly l-lactide:co-glycolide is 85:15.
3. The bioabsorbable polymer composition according to claim 1 , wherein the copolymer is poly l-lactide:d,l-lactide.
4. The bioabsorbable polymer composition according to claim 1 , wherein the copolymer consists of poly l-lactide:co-glycolide and poly l-lactide:d,l-lactide.
5. The bioabsorbable polymer composition according to claim 1 , wherein the copolymer consists of poly l-lactide:co-glycolide.
6. The bioabsorbable polymer according to claim 1 , wherein the ceramic filler consists of about four parts calcium sulphate and three parts tricalcium phosphate.
7. The bioabsorbable polymer composition according to claim 1 , wherein the copolymer is poly l-lactide:co-glycolide.
8. The bioabsorbable polymer composition according to claim 1 , wherein the ratio of poly l-lactide:d,l-lactide is 70:30.
9. A method comprising securing soft tissue to a bone using at least one suture anchor comprising the composition of claim 1 .
10. The method of claim 9 , wherein the soft tissue is selected from the group consisting of ligament, tendon, muscle, and cartilage.
11. The method of claim 9 , wherein the bone is patella bone.
12. The method of claim 9 , wherein the ceramic filler comprises material purified from natural sources.
13. The method of claim 9 , wherein the ceramic filler comprises synthetic material.
14. The method of claim 9 , wherein the ceramic filler comprises a mixture of synthetic material and material purified from natural sources.
15. The method according to claim 9 , wherein the poly l-lactide:co-glycolide is 85:15 l-lactide:co-glycolide.
16. The method according to claim 9 , wherein the poly l-lactide:d,l-lactide is 70:30 poly l-lactide:d,l-lactide.
17. The method according to claim 9 , wherein the ceramic filler is tricalcium phosphate.
18. The method according to claim 9 , comprising 65% polymer and 35% ceramic filler.
19. The method according to claim 18 , wherein the ceramic filler is four parts calcium sulphate and three parts tricalcium phosphate.