IP Library Granted Patent US 8,783,151
Granted Patent B1
US 8,783,151 · App. 14/012,348 · Granted Jul 22, 2014

Methods of manufacturing vascular treatment devices

Inventors: Vallabh Janardhan (Dallas, TX); Vikram Janardhan (Sacramento, CA)
Assignee: Insera Therapeutics, Inc.
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Quick Facts
Patent No.
US 8,783,151
App. No.
14/012,348
Granted
Jul 22, 2014
Kind
B1
Abstract

Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Claims (29)

1. A method of manufacturing a vascular treatment device, the method comprising:

arranging a plurality of spools on a yarn wheel, at least some of the spools comprising radiopaque wires and at least some of the spools comprising shape memory wires;

braiding the radiopaque wires and the shape memory wires in a one-over-one-under-one pattern around a first mandrel to form a textile structure;

shape setting the textile structure in a substantially cylindrical shape;

providing a second mandrel comprising bulbs and necks, wherein the second mandrel comprises the bulbs threaded along a strand;

securing the shape-set textile structure on the second mandrel, wherein securing the shape-set textile structure on the second mandrel comprises wrapping at least one of bangles and c-shaped clamps around the necks of the second mandrel;

shape setting the shape-set textile structure on the second mandrel; and

removing the shape-set textile structure from the second mandrel.

2. The method of claim 1 , wherein securing the shape-set textile structure on the second mandrel comprises wrapping wire around the necks of the second mandrel.

3. The method of claim 1 , wherein the radiopaque wires comprise platinum tungsten wires.

4. The method of claim 1 , wherein the shape memory wires comprise nickel titanium wires.

5. The method of claim 1 , further comprising bonding the shape-set textile structure to a delivery system.

6. The method of claim 5 , wherein bonding the shape-set textile structure to the delivery system comprises inlay bonding.

7. The method of claim 6 , further comprising, before bonding the shape-set textile structure to the delivery system, positioning the wires in a pinch ring or a pinch cylinder.

8. The method of claim 5 , wherein bonding the shape-set textile structure to the delivery system comprises overlay bonding.

9. The method of claim 8 , wherein bonding the shape-set textile structure to the delivery system comprises bonding a proximal end of the shape-set textile structure to a distal end of the delivery system.

10. The method of claim 8 , wherein bonding the shape-set textile structure to the delivery system comprises bonding a distal end of the shape-set textile structure to a distal end of the delivery system.

11. The method of claim 8 , wherein bonding the shape-set textile structure to the delivery system comprises placing a tubing around a bonding area.

12. The method of claim 5 , wherein bonding the shape-set textile structure to the delivery system comprises soldering the shape-set textile structure to the cut hypotube delivery system.

13. The method of claim 5 , wherein the delivery system comprises a cut hypotube.

14. The method of claim 5 , wherein the delivery system comprises a hypotube comprising a first pattern and a second pattern.

15. The method of claim 14 , further comprising:

cutting the first pattern of longitudinally-spaced rows each comprising two kerfs and two stems into the hypotube, the two stems in each of the rows of the first pattern circumferentially opposite, the stems of the first pattern offset in a first circumferential direction; and

cutting the second pattern of longitudinally-spaced rows each comprising two kerfs and two stems into the hypotube, the two stems in each of the rows of the second pattern circumferentially opposite, the stems of the second pattern offset in a second circumferential direction opposite the first circumferential direction, the second pattern singly alternatingly interspersed with the first pattern.

16. The method of claim 15 , wherein cutting the first pattern and cutting the second pattern comprises cutting rounded edges of the kerfs in each of the rows of the first pattern and the second pattern.

17. The method of claim 15 , wherein cutting the first pattern and cutting the second pattern comprises cutting each of the rows of the first pattern and the second pattern at an angle with respect to a longitudinal axis of the hypotube.

18. The method of claim 15 , wherein the hypotube comprises stainless steel.

19. The method of claim 15 , wherein the hypotube comprises nitinol.

20. The method of claim 15 , wherein a pitch of the longitudinally-spaced rows of the first pattern and the second pattern varies longitudinally along the hypotube.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Sep 9, 2021
From: KNOBBE, MARTENS, OLSON & BEAR, LLP
To: INSERA THERAPEUTICS, INC.
Reel/Frame 057454/0677 →
SECURITY INTEREST Recorded Jun 30, 2020
From: INSERA THERAPEUTICS, INC.
To: KNOBBE, MARTENS, OLSON & BEAR, LLP
Reel/Frame 053095/0350 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 3, 2013
From: JANARDHAN, VALLABH; JANARDHAN, VIKRAM
To: INSERA THERAPEUTICS, INC.
Reel/Frame 031125/0033 →
Continuity (3)
Continuation 13953556 · Jul 29, 2013
Continuation In Part 13952982 · Jul 29, 2013
Provisional Application 61798540 · Mar 15, 2013