IP Library Granted Patent US 8,789,452
Granted Patent B1
US 8,789,452 · App. 14/012,904 · Granted Jul 29, 2014

Methods of manufacturing woven vascular treatment devices

Inventors: Vallabh Janardhan (Dallas, TX); Vikram Janardhan (Sacramento, CA)
Assignee: Insera Therapeutics, Inc.
A61B17/221D04C1/12
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Quick Facts
Patent No.
US 8,789,452
App. No.
14/012,904
Granted
Jul 29, 2014
Kind
B1
Abstract

Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measurable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Claims (32)

1. A method of manufacturing a vascular treatment device, the method comprising:

arranging a plurality of spools on spindles on a yarn wheel, at least some of the spools comprising radiopaque wires and at least some of the spools comprising shape memory wires;

attaching an end of each of the wires to a ring over a first mandrel, the first mandrel comprising a substantially cylindrical shape;

braiding the radiopaque wires and the shape memory wires in a one-over-one-under-one pattern around the first mandrel to form a textile structure, wherein braiding comprises rotating the yarn wheel, rotating the spindles, and longitudinally pulling the ring along the first mandrel away from the yarn wheel;

shape setting the textile structure into a substantially cylindrical shape;

securing the shape-set textile structure on a second mandrel comprising bulbs and necks, wherein the second mandrel comprises bulbs threaded along a strand;

shape setting the shape-set textile structure on the second mandrel; and

removing the shape-set textile structure from the second mandrel.

2. The method of claim 1 , wherein securing the shape-set textile structure on the second mandrel comprises wrapping a wire around the necks of the second mandrel.

3. The method of claim 1 , further comprising forming the second mandrel.

4. The method of claim 3 , wherein forming the second mandrel comprises stringing the bulbs along the strand.

5. The method of claim 4 , wherein stringing the bulbs along the strand comprises selecting shapes of the bulbs, sizes of the bulbs, and spacing between the bulbs.

6. The method of claim 1 , wherein arranging the plurality of spools comprises positioning at least two of the spools comprising radiopaque wires adjacent to each other.

7. The method of claim 1 , further comprising bonding the shape-set textile structure to a hypotube.

8. A method of manufacturing a vascular treatment device, the method comprising:

arranging a plurality of spools of wire on spindles on a yarn wheel;

braiding the wires around a mandrel comprising bulbs and necks to form a textile structure, wherein the mandrel comprises bulbs threaded along a strand, and wherein braiding comprises pulling a ring attached to an end of each of the wires away from the yarn wheel;

shape setting the textile structure on the mandrel; and

removing the shape-set textile structure from the mandrel.

9. The method of claim 8 , further comprising securing the textile structure on the mandrel before shape setting.

10. The method of claim 8 , further comprising forming the mandrel.

11. The method of claim 10 , wherein forming the mandrel comprises stringing the bulbs along the strand.

12. The method of claim 11 , wherein stringing the bulbs along the strand comprises selecting shapes of the bulbs, sizes of the bulbs, and spacing between the bulbs.

13. The method of claim 8 , further comprising bonding the shape-set textile structure to a hypotube.

14. The method of claim 1 , wherein the textile structure comprises two sine waves each comprising a radiopaque wire, the two sine waves phase shifted from each other by about 180°.

15. The method of claim 1 , wherein the textile structure comprises three sine waves each comprising a radiopaque wire, the three sine waves phase shifted from each other by about 120°.

16. The method of claim 1 , wherein the textile structure comprises a first sine wave comprising a radiopaque wire, a second sine wave comprising a radiopaque wire, the second sine wave phase shifted from the first sine wave by about 180°, a third sine wave comprising a radiopaque wire, the third sine wave phase shifted from the first sine wave by about 7.5°, and a fourth sine wave comprising a radiopaque wire, the fourth sine wave phase shifted from the third sine wave by about 7.5°.

17. The method of claim 1 , wherein securing the shape-set textile structure on the second mandrel comprises wrapping bangles around the necks of the second mandrel.

18. The method of claim 1 , wherein securing the shape-set textile structure on the second mandrel comprises wrapping c-shaped clamps around the necks of the second mandrel.

19. The method of claim 8 , wherein securing the shape-set textile structure on the second mandrel comprises wrapping a wire around the necks of the second mandrel.

20. The method of claim 8 , wherein securing the shape-set textile structure on the second mandrel comprises wrapping bangles around the necks of the second mandrel.

21. The method of claim 8 , wherein securing the shape-set textile structure on the second mandrel comprises wrapping c-shaped clamps around the necks of the second mandrel.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Sep 9, 2021
From: KNOBBE, MARTENS, OLSON & BEAR, LLP
To: INSERA THERAPEUTICS, INC.
Reel/Frame 057454/0677 →
SECURITY INTEREST Recorded Jun 30, 2020
From: INSERA THERAPEUTICS, INC.
To: KNOBBE, MARTENS, OLSON & BEAR, LLP
Reel/Frame 053095/0350 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 3, 2013
From: JANARDHAN, VALLABH; JANARDHAN, VIKRAM
To: INSERA THERAPEUTICS, INC.
Reel/Frame 031125/0033 →
Continuity (3)
Continuation 13953540 · Jul 29, 2013
Continuation In Part 13952982 · Jul 29, 2013
Provisional Application 61798540 · Mar 15, 2013