Pressure monitoring systems
Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.
1. A tissue treatment system, comprising:
a handle having a housing:
an elongate probe extending from the housing and having a distal tip and a flexible length;
a liner expandably enclosing the probe;
at least one infusion lumen positioned through or along the elongate probe, wherein the infusion lumen defines one or more openings along its length;
at least one delivery lumen slidingly positioned through or along the infusion lumen, wherein proximal translation of the delivery lumen relative to the infusion lumen from a first location increases the number of unobstructed openings, and distal translation of the delivery lumen relative to the infusion lumen from the first location decreases the number of unobstructed openings;
one or more pressure sensors in communication with an interior of the liner; and
a controller in communication with the one or more pressure sensors, wherein the controller is programmed to monitor pressure while a cryoablative fluid or gas is infused into the interior via the infusion lumen such that the cryoablative fluid or gas is sprayed through the unobstructed openings and coats an inner surface of the liner.
2. The system of claim 1 wherein the controller is further programmed to pause the infusion of the cryoablative fluid or gas when the monitored pressure exceeds 150 mmHg.
3. The system of claim 1 further comprising one or more actuatable valves in communication with the controller, wherein the one or more actuatable valves are configured to stop the infusion of the cryoablative fluid when triggered by the controller.
4. The system of claim 1 wherein the one or more pressure sensors are positioned along the elongate probe for monitoring the pressure within the interior of the liner.
5. The system of claim 1 wherein the one or more pressure sensors are positioned near or at a tip of the elongate probe.
6. The system of claim 1 wherein the one or more pressure sensors are positioned to be in fluid communication with the infusion lumen.
7. The system of claim 1 further comprising one or more flow sensors in communication with the controller.
8. The system of claim 1 wherein a delivery line in fluid communication with the infusion lumen is sized to limit a flow rate through the delivery line.
9. The system of claim 1 further comprising one or more temperature sensors which are in communication with the controller.
10. The system of claim 1 further comprising an indicator or alarm in communication with the controller, wherein the indicator or alarm is configured to alert a user when a predetermined pressure is exceeded within the interior of the liner.
11. The system of claim 1 wherein the controller is further programmed to transmit a signal on a regular basis to the system.
12. The system of claim 1 further comprising a relief valve in communication with the interior of the liner, wherein the relief valve is configured to open if a predetermined pressure is exceeded.
13. The system of claim wherein the controller is further programmed to detect whether the pressure within the interior of the liner deviates by 20 mmHg or more over a period of 3 seconds to determine whether a leak is present within the liner.
14. The system of claim 1 wherein the controller is further programmed to infuse the cryoablative fluid or gas at a predetermined temperature or pressure of the interior of the liner.
15. The system of claim 1 wherein the cryoablative fluid or gas comprises nitrous oxide or argon.
16. The system of claim 1 further comprising a pump in fluid communication with the liner interior.