Synergistic antimicrobial composition
View Patent ↗A synergistic antimicrobial composition comprising: (a) a hydroxymethyl-substituted phosphorus compound selected from the group consisting of tetrakis(hydroxymethyl)phosphonium salts and tris(hydroxymethyl)phosphine; and (b) tris(hydroxymethyl)nitromethane.
1. A method for inhibiting microbial growth in a medium at a temperature of at least 60° C. and a sulfide level at least 4 ppm; said method comprising adding to the medium: (a) tetrakis(hydroxymethyl)phosphonium sulfate; and (b) tris(hydroxymethyl)nitromethane; wherein a weight ratio of tetrakis(hydroxymethyl)phosphonium sulfate to tris(hydroxymethyl)nitromethane is from 1:2 to 1:8.
2. The method of claim 1 in which the temperature is at least 70° C. and a sulfide level at least 7 ppm; and in which said weight ratio is from 1:2 to 1:8.
3. The method of claim 2 in which the medium is anaerobic and contains sulfate-reducing bacteria.