IP Library Granted Patent US 9,826,958
Granted Patent B2
US 9,826,958 · App. 14/044,842 · Granted Nov 28, 2017

Automated detection of suspected abnormalities in ultrasound breast images

Inventors: Wei Zhang (San Jose, CA); Shih-Ping Wang (Los Altos, CA); Alexander Schneider (Los Altos, CA); Nico Karssemeijer (Beek-Ubbergen, NL)
Assignee: QView, INC
A61B8/0825A61B8/5238G06T7/0012G06T2207/10132G06T2207/30068
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Quick Facts
Patent No.
US 9,826,958
App. No.
14/044,842
Granted
Nov 28, 2017
Kind
B2
Abstract

A method and system for processing and displaying breast ultrasound information is described. A 2D feature weighted volumetric coronal image as a “guide” or “road map” is generated from the 3D ultrasound data volume to represent the 3D dataset with the goal of emphasizing abnormalities within the breast while excluding non-breast structures, particularly those external to the breast such as ribs and chest wall.

Claims (11)

1. A method of operating an ultrasound breast imaging system, comprising:

acquiring a three-dimensional (3D) breast ultrasound image with a 3D breast ultrasound acquisition system by a chestward compression scan of a patient's breast;

detecting skin, chestwall, and ribs in the 3D ultrasound image with a computer processor;

segmenting a portion of the 3D breast ultrasound image that excludes the detected skin, chestwall, and ribs;

filtering the segmented portion of the 3D breast ultrasound image to suppress noise and enhance lesions therein by using a computer processor to apply thereto a gradient conversion filter f 1 that enhances dark rounded shapes in the breast, a line conversion filter f 2 that enhances lines radiating from a center and resemble a speculation or architectural distortion in the breast, and a computer-aided detection filter f 3 algorithm, and generating compounding weights w(x,y,z) by combining outputs of the filters f 1 , f 2 , and f 3 , where (x,y,z) designates respective 3D locations of voxels in the segmented portion of the 3D ultrasound image;

normalizing the weights w(x,y,z) for a probability of voxel overlap with a cancer lesion;

producing only one composite coronal guide two-dimensional (2D) image for said chestward compression scan of the breast by forming a 2D atlas image through projecting, with a computer processor, the segmented portion of the 3D breast ultrasound image modulated by the normalized compounding weights w(x,y,z);

displaying the composite coronal guide 2D image on a computer monitor coupled with the computer processor; and

causing the computer processor to respond to pointing to a lesion in the displayed composite coronal guide 2D image to automatically bring up on the display an additional image from said chestward compression scan, which additional image contains the pointed to lesion.

2. The method of claim 1 , in which said additional image is an original 2D axial slice image taken in said acquiring step.

3. The method of claim 1 , in which the acquiring step takes additional 3D breast ultrasound images by additional chestward compression scans of the patient's breast, and the remaining steps of the method are applied to each of the additional images, thereby producing and displaying a respective single composite coronal guide 2D image for each of said additional chestward compression scans.

Assignments (4)
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT APPL. NO. 12/839,917 PREVIOUSLY RECORDED AT REEL: 034445 FRAME: 0969. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Oct 17, 2017
From: ZHANG, WEI; WANG, SHIH-PING; SCHNEIDER, ALEXANDER; ROMSDAHL, HARLAN; NEFF, THOMAS
To: QVIEW, MEDICAL INC.
Reel/Frame 044217/0709 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 10, 2015
From: ZHANG, WEI; WANG, SHIH-PING; SCHNEIDER, ALEXANDER; NEFF, THOMAS
To: QVIEW MEDICAL, INC.,
Reel/Frame 034930/0920 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 24, 2014
From: ZHANG, WEI; WANG, SHIH-PING; SCHNEIDER, ALEXANDER; ROMSDAHL, HARLAN; NEFF, THOMAS
To: QVIEW, MEDICAL INC
Reel/Frame 034445/0969 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2014
From: ZHANG, WEI; WANG, SHIH-PING; SCHNEIDER, ALEXANDER; KARSSEMEIJER, NICO
To: QVIEW, INC.,
Reel/Frame 032351/0493 →
Continuity (7)
Continuation In Part 12839371 · Jul 19, 2010
Continuation In Part PCTUS2009066020 · Nov 27, 2009
Provisional Application 61860900 · Jul 31, 2013
Provisional Application 61830241 · Jun 3, 2013
Provisional Application 61728166 · Nov 19, 2012
Provisional Application 61709136 · Oct 2, 2012
Related Publication 20140039318A1 · Feb 6, 2014