Granted Patent
B2
US 9,308,273 · App. 14/045,489 · Granted Apr 12, 2016
Polymer derivatives comprising an acetal or ketal branching point
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Abstract
The invention conjugates that can be prepared by contacting a polymer comprising an acetal or ketal branching point with a pharmacologically active agent under conditions suitable to form a covalent attachment between the polymer and the pharmacologically active agent.
Claims (3)
1. A conjugate prepared by a polymer with a pharmacologically active agent under conditions suitable to form a covalent attachment between the polymer and the pharmacologically active agent, wherein the polymer is selected from the group consisting of
wherein each (m) is from 2 to 4,000 and R o is H or an organic radical.
2. The conjugate of claim 1 , wherein the pharmacologically active agent is selected from the group consisting of peptides, polypeptides and proteins.
Assignments (4)
RELEASE OF SECURITY INTEREST
Recorded Apr 17, 2020
From: TC LENDING, LLC, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 053180/0009 →
RELEASE OF SECURITY INTEREST RECORDED AT REEL 31838, FRAME 0343
Recorded Oct 14, 2015
From: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 036876/0138 →
GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS
Recorded Oct 6, 2015
From: NEKTAR THERAPEUTICS
To: TC LENDING, LLC, AS COLLATERAL AGENT
Reel/Frame 036796/0562 →
SECURITY AGREEMENT
Recorded Dec 18, 2013
From: NEKTAR THERAPEUTICS
To: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 031838/0343 →