IP Library › Patent Application 14046847
Patent Application
App. No. 14/046,847

METHOD OF PREVENTING AND TREATING HEPATIC DISEASE USING A2B ADENOSINE RECEPTOR ANTAGONISTS

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Quick Facts
Patent No.
US None
App. No.
14/046,847
Abstract

The invention is related to methods of preventing and treating hepatic fibrosis using A 2B adenosine receptor antagonists and utility in the treatment and prevention of liver damage caused by alcohol abuse, surgical intervention, viral hepatitis, the ingestion of hepatotoxic drugs, or other hepatic diseases. The invention also relates to pharmaceutical compositions for use in the method.

Claims (6)

1 - 21 . (canceled)

22 . A method of treating viral hepatitis by administering a therapeutically effective amount of a compound having the name 3-ethyl-1-propyl-8-(1-{[3-(trifluoromethyl)phenyl]methyl}pyrazol-4-yl)-1,3,7-trihydropurine-2,6-dione and the chemical formula

or a pharmaceutically acceptable salt thereof.

23 . The method of claim 22 , wherein the compound is administered orally.

24 . The method of claim 22 , wherein the compound is administered by IV.

25 . The method of claim 22 , wherein the mammal is human.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2013
From: GILEAD PALO ALTO, INC.
To: GILEAD SCIENCES, INC.
Reel/Frame 031864/0586 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 11, 2013
From: ZENG, DEWAN; ZHONG, HONGYAN; BELARDINELLI, LUIZ
To: CV THERAPEUTICS, INC.
Reel/Frame 031763/0001 →
MERGER Recorded Dec 11, 2013
From: APEX MERGER SUB, INC.; CV THERAPEUTICS, INC.
To: GILEAD PALO ALTO, INC.
Reel/Frame 031763/0205 →