Topical anti-inflammatory combination
View Patent ↗Provided, among other things, is a method of treating or ameliorating an indication of non-mucosal topical tissue comprising periodically applying to such disease affected tissue a composition comprising: an effective amount of an appropriate composition of herbal bioactive comprising active(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea , and an effective amount of a quaternary ammonium surfactant.
1. A method of treating or ameliorating an indication of non-mucosal topical tissue that is contact or atopic dermatitis; impetiginized eczema; nummular eczema; endogenous chronic infectious dermatitis; stasis dermatitis; pyoderma; nuchal eczema; chronic eczematoid otitis externa; localized or disseminated neurodermatitis; lichen simplex chronicus; anogenital pruritus; folliculitis; bacterial dermatoses; mycotic dermatoses; moniliasis; intertrigo; pseudomonas infections; ecthyma, candidiasis; herpes simplex lesions; dermatophytoses; staphylococcal infections; proctitis; hidradenitis suppurativa; rhinitis; sinusitis; scabies; cutaneous larva migrans; tinea; urinary tract infections; or cutaneous penile lesions,
comprising periodically applying to such disease affected tissue a composition comprising
an effective amount of an appropriate composition of herbal extract(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea , and
an effective amount of a quaternary ammonium surfactant, wherein the quaternary ammonium surfactant comprises a 1-alkylpyridinium salt, where alkyl is C8-C36.
2. The method of claim 1 , further comprising applying to a portion of the tissue a film, patch or an adhesive solid formulation comprising appropriate composition of herbal extract(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea.
3. The method of claim 1 , wherein the extract(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea comprise an antiinflammatory amount.
4. The method of claim 1 ,
wherein Sambucus nigra extract is more than 50% to 90% by weight of the plant extract solids and Centella asiatica is 1% to less than 50% by weight of the plant extract solids, and
the surfactant is a 1-alkylpyridinium salt, where alkyl is C8-C36, the surfactant present in an amount from 0.01 to 5% of the formulation by weight.
5. The method of claim 4 , further comprising applying to a portion of the tissue a film, patch or an adhesive solid formulation comprising appropriate composition of herbal extract(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea.
6. The method of claim 1 , wherein the indication of non-mucosal topical tissue is
contact or atopic dermatitis;
impetiginized eczema;
nummular eczema;
stasis dermatitis;
nuchal eczema;
localized or disseminated neurodermatitis;
lichen simplex chronicus;
proctitis;
hidradenitis suppurativa;
sinusitis; or
cutaneous penile lesions.
7. The method of claim 6 , further comprising applying to a portion of the tissue a film, patch or an adhesive solid formulation comprising appropriate composition of herbal extract(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea.
8. The method of claim 6 , wherein the extract(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea comprise an antiinflammatory amount.
9. The method of claim 6 ,
wherein Sambucus nigra extract is more than 50% to 90% by weight of the plant extract solids and Centella asiatica is 1% to less than 50% by weight of the plant extract solids, and
the surfactant is a 1-alkylpyridinium salt, where alkyl is C8-C36, the surfactant present in an amount from 0.01 to 5% of the formulation by weight.
10. The method of claim 9 , further comprising applying to a portion of the tissue a film, patch or an adhesive solid formulation comprising appropriate composition of herbal extract(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea.
11. The method of claim 1 , wherein the indication of non-mucosal topical tissue is contact or atopic dermatitis.
12. The method of claim 1 , wherein the indication of non-mucosal topical tissue is anogenital pruritus.
13. The method of claim 1 , wherein the indication of non-mucosal topical tissue is herpes simplex lesions.
14. A method of treating or ameliorating a non-mucosal wound comprising periodically applying to the wound a composition comprising
an effective amount of an appropriate composition of herbal extract(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea , and
an effective amount of a quaternary ammonium surfactant that comprises a 1-alkylpyridinium salt, where alkyl is C8-C36.
15. The method of claim 14 , further comprising applying to a portion of the tissue a film, patch or an adhesive solid formulation comprising appropriate composition of herbal extract(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea.
16. The method of claim 14 , wherein the extract(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea comprise an antiinflammatory amount.
17. The method of claim 14 ,
wherein Sambucus nigra extract is more than 50% to 90% by weight of the plant extract solids and Centella asiatica is 1% to less than 50% by weight of the plant extract solids, and
the surfactant present in an amount from 0.01 to 5% of the formulation by weight.
18. The method of claim 17 , further comprising applying to a portion of the tissue a film, patch or an adhesive solid formulation comprising appropriate composition of herbal extract(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea.