IP Library › Granted Patent US 9,238,000
Granted Patent B2
US 9,238,000 · App. 14/055,037 · Granted Jan 19, 2016

Method of improving aging appearance of skin by modulation of WIPI-1

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Quick Facts
Patent No.
US 9,238,000
App. No.
14/055,037
Granted
Jan 19, 2016
Kind
B2
Abstract

Methods of using WIPI-1 to impart anti-aging benefits to the skin and/or improve skin conditions resulting from reduced autophagy activity.

Claims (1)

1. A method for improving the aesthetic appearance of skin of a human affected by aging resulting from reduced autophagy activity within skin cells of the human comprising topically applying thereto a therapeutically effective amount of an extract of Tiliacora triandra that upregulates WIPI-1 in vitro by greater than 60% when applied to fibroblasts at a concentration of 0.1% (w/w) in a cosmetically acceptable vehicle for a time sufficient to achieve an improvement in the appearance of said skin of said human.

Assignments (4)
SECURITY INTEREST Recorded Nov 14, 2019
From: AVON PRODUCTS, INC.
To: CITIBANK, N.A., LONDON BRANCH
Reel/Frame 051032/0210 →
RELEASE OF SECURITY INTEREST IN PATENTS Recorded Aug 15, 2016
From: CITIBANK, N.A.
To: AVON PRODUCTS, INC.
Reel/Frame 039690/0331 →
SECURITY INTEREST Recorded Jun 12, 2015
From: AVON PRODUCTS, INC.
To: CITIBANK, N.A.
Reel/Frame 035899/0776 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 16, 2013
From: KHUSIAL, PERMANAN RAAJ; SANTHANAM, UMA; LYGA, JOHN W.
To: AVON PRODUCTS, INC.
Reel/Frame 031414/0679 →