IP Library Granted Patent US 9,101,574
Granted Patent B2
US 9,101,574 · App. 14/059,025 · Granted Aug 11, 2015

Cyclosporin compositions

Inventors: James N. Chang (Newport Beach, CA); Orest Olejnik (Coto de Caza, CA); Bruce A. Firestone (Irvine, CA)
Assignee: Allergan, Inc.
A61K38/13A61K9/0048A61K9/107
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Quick Facts
Patent No.
US 9,101,574
App. No.
14/059,025
Granted
Aug 11, 2015
Kind
B2
Abstract

A composition is disclosed herein comprising from about 0.001% to about 0.4% cyclosporin A, castor oil, and a surfactant selected from the group consisting of alcohol ethoxylates, alcohols, alkyl glycosides, alkyl polyglycosides, alkylphenol ethoxylates, amine oxides, block polymers, carboxylated alcohol or alkylphenol ethoxylates, carboxylic acids/fatty acids, cellulose derivatives, ethoxylated alcohols, ethoxylated alkylphenols, ethoxylated aryl phenols, ethoxylated fatty acids, ethoxylated fatty acids, ethoxylated fatty esters and oils, fatty alcohols, fatty esters, glycol esters, lanolin-based derivatives, lecithin and lecithin derivatives, lignin and lignin derivatives, methyl esters, monoglycerides and derivatives, phosphalipids, polyacrylic acids, polyethylene glycols, polyethylene oxide-polypropylene oxide copolymers, polyethylene oxides, polymeric surfactants, polypropylene oxides, propoxylated alcohols, propoxylated alkyl phenols, propoxylated fatty acids, protein-based surfactants, sarcosine derivatives, silicone-based surfactants, sorbitan derivatives, stearates, sucrose and glucose esters and derivatives, and combinations thereof.

Claims (1)

1. An ophthalmically acceptable emulsion comprising from about 0.001% to 0.4% cyclosporin A, castor oil, Polysorbate 80, Pemulen, and a cellulose derivative selected from the group consisting of hydroxypropylmethyl cellulose and carboxymethyl cellulose.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2017
From: ALLERGAN, INC.
To: SAINT REGIS MOHAWK TRIBE
Reel/Frame 043830/0446 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 14, 2014
From: CHANG, JAMES N.; OLEJNIK, OREST; FIRESTONE, BRUCE A.
To: ALLERGAN, INC.
Reel/Frame 031967/0122 →
Continuity (5)
Continuation 13536479 · Jun 28, 2012
Continuation 11857223 · Sep 18, 2007
Division 11255821 · Oct 19, 2005
Continuation In Part 11181409 · Jul 13, 2005
Related Publication 20140045772A1 · Feb 13, 2014