IP Library Granted Patent US 8,873,824
Granted Patent B2
US 8,873,824 · App. 14/064,319 · Granted Oct 28, 2014

Breast tomosynthesis with display of highlighted suspected calcifications

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Quick Facts
Patent No.
US 8,873,824
App. No.
14/064,319
Granted
Oct 28, 2014
Kind
B2
Abstract

Systems and methods that facilitate the presentation and assessment of selected features in projection and/or reconstructed breast images, such as calcifications that meet selected criteria of size, shape, presence in selected slice images, distribution of pixels that could be indicative of calcification relative to other pixels or of other image features of clinical interest.

Claims (32)

1. A method of acquiring and displaying x-ray images, comprising:

acquiring x-ray image data representing projection images taken at different angles of an origin of imaging x-rays relative to a patient's breast;

generating tomosynthesis image data from the acquired x-ray image data, wherein the tomosynthesis image data comprises image slices of the patient's breast, each image slice having an orientation and a thickness; and

displaying one or more of the image slices,

wherein at least one of the displayed one or more image slices includes an indicator identifying a feature of interest in the respective displayed image slice.

2. The method of claim 1 , wherein the indicator comprises a mark adjacent the feature of interest.

3. The method of claim 2 , wherein the mark is selected from the group consisting of a dot, an arrow, a circle, a square, and a line.

4. The method of claim 2 , wherein the mark surrounds the feature of interest.

5. The method of claim 1 , wherein the indicator comprises an enhanced brightness of the feature of interest.

6. The method of claim 1 , wherein the indicator comprises an enhanced size of the feature of interest.

7. The method of claim 1 , wherein the indicator comprises a color of the feature of interest.

8. The method of claim 1 , wherein the indicator comprises an area of enhanced brightness adjacent the feature of interest.

9. The method of claim 1 , wherein the indicator comprises a colored area adjacent the identified feature of interest.

10. The method of claim 1 , wherein the indicator comprises a directional indicator indicating a direction that is non-parallel to a plane of the respective displayed image slice.

11. The method of claim 1 , wherein displaying one or more of the image slices comprises displaying all image slices of the patient's breast contained in the tomosynthesis image data.

12. The method of claim 1 , where the x-ray image data comprises at least one of x-ray tomosynthesis image data Tp and x-ray mammography image data Mp.

13. A method of acquiring and displaying x-ray images, comprising:

acquiring x-ray image data representing projection images taken at different angles of an origin of imaging x-rays relative to a patient's breast;

generating tomosynthesis image data from the acquired x-ray image data, wherein the tomosynthesis image data comprises image slices of the patient's breast, each image slice having an orientation and a thickness;

processing at least one of the x-ray image data and the tomosynthesis image data to identify a feature of interest; and

displaying one or more of the image slices,

wherein at least one of the one or more displayed image slices includes an indicator identifying the feature of interest.

14. The method of claim 13 , wherein processing at least one of the x-ray image data and the tomosynthesis image data comprises processing both the x-ray image data and the tomosynthesis image data.

15. The method of claim 13 , wherein the indicator comprises a mark adjacent the feature of interest.

16. The method of claim 13 , wherein the indicator comprises an enhanced brightness of the feature of interest.

17. The method of claim 13 , wherein the indicator comprises a color of the feature of interest.

18. The method of claim 13 , wherein displaying one or more of the image slices comprises displaying all image slices of the patient's breast contained in the x-ray image data and tomosynthesis image data.

19. A method of acquiring and displaying x-ray images, comprising:

acquiring x-ray image data representing projection images taken at different angles of an origin of imaging x-rays relative to a patient's breast;

generating tomosynthesis image data from the acquired x-ray image data, wherein the tomosynthesis image data comprises image slices of the patient's breast, each image slice having an orientation and a thickness; and

displaying a plurality of the image slices,

wherein a first displayed image slice includes an indicator identifying a feature of interest in a second displayed image slice adjacent to the first displayed image slice.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Apr 28, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC., ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO DIRECT RADIOGRAPHY CORP.; CYTYC CORPORATION, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO BIOLUCENT, LLC; CYTYC SURGICAL PRODUCTS, LLC, AS SUCCESSOR-BY-CONVERSION TO CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; GEN-PROBE INCORPORATED, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.
Reel/Frame 075566/0039 →
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
SECURITY AGREEMENT Recorded Aug 7, 2015
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 036307/0199 →
SECURITY INTEREST RELEASE REEL/FRAME 032059 0467 Recorded Jul 17, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; SUROS SURGICAL SYSTEMS, INC.; BIOLUCENT, LLC; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 036126/0813 →
SECURITY AGREEMENT Recorded Jan 16, 2014
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED; DIRECT RADIOGRAPHY CORP.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 032059/0467 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 21, 2013
From: RUTH, CHRIS; STEIN, JAY; NIKLASON, LOREN; SMITH, ANDREW
To: HOLOGIC, INC.
Reel/Frame 031647/0043 →