Circuit for biological liquid
View Patent ↗The invention concerns a circuit comprising a bag ( 111 ) comprising two flexible films ( 145, 146 ) and routing network connectors, and a press ( 110 ) comprising a first shell ( 114 ) and a second shell ( 113 ) clamping the bag to form pipes ( 104 ) between the films, the first shell comprising a pinch valve ( 120 ) which comprises an actuator ( 121 ) comprising a movable member ( 124 ) and in register with the moveable member an elastically compressible pad ( 131 ) which, when the valve is in an open position, has a resting configuration in which a second face ( 33 ) of the pad is concave and locally delimits a shaping channel ( 118 ), and, when the valve is in a closed position, has a pinching configuration in which the second face ( 133 ) is convex, with the pipe and the pad sandwiched between a shaping channel ( 116 ) and the moveable member.
1. A circuit for biological liquid, comprising a plurality of routing connectors ( 2 ) and a network ( 3 ; 103 ) for routing liquid between said connectors, comprising:
a bag ( 11 ; 111 ) comprising two flexible films ( 45 , 46 ; 145 , 146 ) and said routing network connectors ( 2 ); and
a press ( 10 ; 110 ) comprising a first shell ( 14 ; 114 ) and a second shell ( 13 ; 113 ) clamping said bag ( 11 ; 111 ) in a state in which pipes ( 4 ; 104 ) of said liquid routing network ( 3 ; 103 ) are formed between said films ( 45 , 46 ; 145 , 146 ), said first shell ( 14 ; 114 ) comprising for each of said pipes ( 4 ; 104 ) a shaping channel ( 18 ; 118 ), said second shell ( 13 ; 113 ) comprising for each of said pipes ( 4 ; 104 ) a shaping channel ( 16 ; 116 ) facing a corresponding shaping channel ( 18 ; 118 ) of the first shell ( 14 ; 114 ); with said first shell ( 14 ; 114 ) comprising at least one pinch valve ( 20 ; 120 ) for one of said pipes ( 4 ; 104 ), wherein the valve ( 20 ; 120 ) comprises an actuator ( 21 ; 121 ) comprising a movable pinching member ( 24 ; 124 ), wherein the valve ( 20 ; 120 ) has an open position in which the moveable member ( 24 ; 124 ) is in a retracted position in which it does not pinch the pipe ( 4 ; 104 ) and has a closed position in which the moveable member ( 24 ; 124 ) is in an extended position in which it pinches the pipe ( 4 ; 104 );
said valve ( 20 ; 120 ) further comprising, in register with said moveable pinching member ( 24 ; 124 ), an elastically compressible pad ( 31 ; 131 ), wherein the pad ( 31 ; 131 ) has a first face ( 32 ; 132 ) nearest the moveable member ( 24 ; 124 ) and a second face ( 33 ; 133 ) nearest the pipe corresponding to said pinching member ( 4 ; 104 ), wherein the pad ( 31 ; 131 ), when the valve ( 20 ; 120 ) is in an open position, has a resting configuration in which said second face ( 33 ; 133 ) is concave and locally delimits the first shell shaping channel ( 18 ; 118 ) of the pipe corresponding to said pinching member ( 4 ; 104 ), and, when the valve ( 20 ; 120 ) is in a closed position, has a pinching configuration in which said second face ( 33 ; 133 ) is convex, with said pipe ( 4 ; 104 ) and said pad ( 31 ; 131 ) sandwiched between the second shell shaping channel ( 16 ; 116 ) of the pipe corresponding to said pinching member ( 4 ; 104 ) and the moveable pinching member ( 24 ; 124 ); wherein said pad ( 131 ) forms part of an individual local plate ( 130 ).
2. A circuit according to claim 1 , wherein said pad ( 131 ) forms a central portion of said individual local plate ( 130 ), which comprises lateral ( 171 ) and transverse ( 172 ) walls which surround said central portion.
3. A circuit according to claim 1 , wherein said pipe corresponding to said pinching member ( 4 ; 104 ) has an elliptical contour.
4. A circuit according to claim 1 , wherein said first shell ( 114 ) comprises a recessed accommodation ( 160 ) adapted to receive said pad ( 131 ) at least partially.
5. A circuit according to claim 1 , wherein said pad ( 31 ; 131 ) is fastened to said first shell ( 14 ; 114 ).
6. A circuit according to claim 5 , wherein said pad ( 31 ; 131 ) comprises fastening lugs ( 34 , 35 ; 173 ) which fasten by complementarity of shape in corresponding apertures ( 36 , 37 ; 164 ) of said first shell ( 14 , 114 ).
7. A circuit according to claim 1 , wherein said pad ( 31 ; 131 ) is formed from elastically compressible flexible plastic molded in one piece.
8. A circuit according to claim 1 , wherein said pad ( 31 ; 131 ) is made of silicone.
9. A circuit according to claim 1 , wherein the moveable member of the actuator ( 21 ) comprises a pneumatic membrane ( 24 ) adapted to push said pad ( 31 ) towards the second shell shaping channel ( 16 ).
10. A circuit according to claim 1 , wherein the moveable member of the actuator ( 121 ) comprises a finger ( 124 ) having an end shaped like the second shell shaping channel ( 116 ).
11. A circuit according to claim 1 , wherein at least one of said first and second shells comprises at least one sensor ( 22 ) of a physico-chemical quantity.
12. A circuit according to claim 11 , wherein said sensor ( 22 ) and said pad ( 31 ) are disposed on said first shell ( 14 ).