IP Library Granted Patent US 9,393,281
Granted Patent B2
US 9,393,281 · App. 14/094,251 · Granted Jul 19, 2016

Composition of beta-glucan and ashwagandha

Inventor: Peter S. McNeary (Brattleboro, VT)
Assignees: Nutragenesis, LLC; Natreon, Inc.
A61K36/81A61K31/716
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Quick Facts
Patent No.
US 9,393,281
App. No.
14/094,251
Granted
Jul 19, 2016
Kind
B2
Abstract

Compositions including combinations of β-glucan and Withania somnifera for increasing the immune activity of certain target cytokines and phagocytosis, and reducing cortisol or corticosterone. Methods of improving immunity activity under periods of stress including chronic stress with a combination of β-glucan and Withania somnifera are also described. Particular combinations of β-glucan and Withania somnifera synergistically increases the immune activity of the cytokines IL-12 and IL-6 over expected values.

Claims (3)

1. A therapeutic composition of Withania somnifera and β-glucan consisting essentially of a therapeutically effective combination of Withania somnifera and β-glucan, wherein said Withania somnifera and said β-glucan are a therapeutically effective combination for increasing cytokine production within an animal and reducing cortisol or corticosterone within the animal, further wherein said Withania somnifera and said β-glucan are present in said composition in a weight ratio of about 5.6:94.4 β-glucan to Withania somnifera.

2. A therapeutic composition according to claim 1 , wherein said cytokines include a cytokine selected from the group consisting of IL-6, IL-12, and IFN-γ, and any combinations thereof.

3. A therapeutic composition according to claim 1 , wherein said composition increases phagocytosis.

Assignments (8)
SECURITY INTEREST Recorded Jan 6, 2025
From: INNOPHOS, LLC
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT
Reel/Frame 069749/0211 →
CHANGE OF NAME Recorded Mar 13, 2020
From: NOVEL INGREDIENT SERVICES, LLC
To: INNOPHOS, LLC
Reel/Frame 052164/0808 →
MERGER Recorded Feb 20, 2020
From: NUTRAGENESIS, LLC
To: NOVEL INGREDIENT SERVICES, LLC
Reel/Frame 051876/0164 →
PATENT SECURITY AGREEMENT (TL) Recorded Feb 10, 2020
From: INNOPHOS, INC.; INNOPHOS, LLC
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 051858/0161 →
PATENT SECURITY AGREEMENT (ABL) Recorded Feb 10, 2020
From: INNOPHOS, INC.; INNOPHOS, LLC
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 051858/0131 →
RELEASE OF SECURITY INTEREST Recorded Feb 7, 2020
From: WELLS FARGO BANK, NATIONAL ASSOCIATION
To: NUTRAGENESIS, LLC
Reel/Frame 051749/0764 →
SECURITY INTEREST Recorded Jan 17, 2018
From: NUTRAGENESIS, LLC
To: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
Reel/Frame 044645/0115 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 2, 2013
From: MCNEARY, PETER S
To: NUTRAGENESIS, LLC
Reel/Frame 031700/0040 →
Continuity (3)
Division 13532338 · Jun 25, 2012
Provisional Application 61501029 · Jun 24, 2011
Related Publication 20140087009A1 · Mar 27, 2014