Dental composition
View Patent ↗Dental compositions are disclosed. A dental composition can include a reaction produce of a reaction mixture comprising a first mixture and a second mixture. The first mixture can include a ceramic based biomaterial, and the second mixture can include mineral trioxide aggregate and a phosphoric acid monomer.
1. A dental composition for a dental implant insertable into an implant site, comprising:
a reaction product of a reaction mixture comprising:
a first mixture comprising:
a ceramic based biomaterial including hydroxyapatite,
a diluent comprising a cross-linking agent, and
a first initiator, and
a second mixture comprising:
mineral trioxide aggregate reacts with moisture at the implant site to form a solid scaffold on the dental implant,
a phosphoric acid monomer reacts with the ceramic based biomaterial and the mineral trioxide aggregate to bond the ceramic based biomaterial to the solid scaffold of mineral trioxide aggregate, and
a second initiator;
wherein the diluent reacts with the phosphoric acid monomer to crosslink at least the phosphoric acid monomer.
2. The dental composition of claim 1 , wherein the ceramic based biomaterial further includes one or more of calcium phosphates, strontium phosphates, calcium carbonates, calcium sulfate, and calcium hydroxide.
3. The dental composition of claim 1 , wherein about 50 weight percent to about 80 weight percent of the first mixture comprises the ceramic based biomaterial, the weight percent based on a total weight of the first mixture.
4. The dental composition of claim 1 , wherein 60 weight percent of the first mixture comprises the ceramic based biomaterial, the weight percent based on a total weight of the first mixture.
5. The dental composition of claim 1 , wherein about 5 weight percent to about 50 weight percent of the second mixture comprises the mineral trioxide aggregate, the weight percent based on a total weight of the second mixture.
6. The dental composition of claim 1 , wherein the phosphoric acid monomer is chosen from at least one of 1-methacryloyloxydecane-10-phosphate, 1-methacryloyloxyhexane-6-phosphate, 1-methacryloylaminodecane-10-phosphate, 1-acryloylaminohexane-6-phosphate, 1,3-dimethacryloyloxypropane-2-phosphate, and 1,3-dimethacryloylaminopropane-2-phosphate.
7. The dental composition of claim 1 , wherein about 1 weight percent to about 15 weight percent of the second mixture comprises the phosphoric acid monomer, the weight percent based on a total weight of the second mixture.
8. The dental composition of claim 1 , wherein the first mixture comprises about 15 weight percent to about 55 weight percent of the diluent, the weight percent based on a total weight of the first mixture.
9. The dental composition of claim 1 , wherein the first mixture comprises about 2 weight percent to about 8 weight percent of N,N-di(2-hydroxyethyl)-p-toluidine as the first initiator, the weight percent based on a total weight of the first mixture.
10. The dental composition of claim 1 , wherein the second mixture further comprises about 10 weight percent to about 50 weight percent of a bioactive glass, the weight percent based on a total weight of the second mixture.
11. The dental composition of claim 1 , wherein the second initiator includes a peroxide comprising about 0.5 weight percent to about 6 weight percent of the second mixture, the weight percent based on a total weight of the second mixture.
12. The dental composition of claim 1 , wherein the first mixture comprises:
60 weight percent of hydroxyapatite;
35 weight percent of the diluent; and
5 weight percent of the first initiator, wherein the first initiator comprises N,N-di(2-hydroxyethyl)p-toluidine, the weight percent based on a total weight of the first mixture.
13. The dental composition of claim 12 , wherein the diluent is tetra-ethylene glycol dimethacrylate.
14. The dental composition of claim 1 , wherein the second mixture comprises:
25 weight percent of the mineral trioxide aggregate;
5 weight percent of the phosphoric acid monomer;
3 weight percent of the second initiator, wherein the second initiator comprises a peroxide;
and further comprises 37 weight percent of a diluent and
30 weight percent of a bioactive glass, the weight percent based on a total weight of the second mixture.
15. The dental composition of claim 14 , wherein the diluent of a second mixture is tetra-ethylene glycol dimethacrylate, the peroxide is benzoyl peroxide, and the bioactive glass has a formulation of 46.1 mole percent of silicon dioxide, 2.6 mole percent of phosphorus pentoxide, 26.9 mole percent of calcium oxide, and 24.4 mole percent of sodium oxide.
16. A method, comprising:
obtaining or providing the first mixture of claim 1 ;
obtaining or providing the second mixture of claim 1 ; and
combining the first mixture and the section mixture to form the reaction product of claim 1 .
17. The method of claim 16 , wherein obtaining or providing the first mixture comprises: combining the ceramic based biomaterial with the diluent and N,N-di(2-hydroxyethyl)-p-toluidine as the first initiator.
18. The method of claim 17 , wherein obtaining or providing the first mixture comprises:
dissolving the N,N-di(2-hydroxyethyl)-p-toluidine in the diluent to form a first solution; and
mixing the first solution with the ceramic based biomaterial to form the first mixture.
19. The method of claim 18 , wherein the diluent of the first mixture is a first diluent, and wherein obtaining or providing the second mixture comprises: combining the mineral trioxide aggregate and the phosphoric acid monomer with a second diluent, and a peroxide as the second initiator and further combining with a bioactive glass.
20. The method of claim 16 , wherein obtaining or providing the second mixture comprises:
dissolving the phosphoric acid monomer and the peroxide in the diluent to form a second solution; and
mixing the second solution with the mineral trioxide aggregate and further mixing with a bioactive glass to form the second mixture.