Method of using a control solution and preparing for testing using the same
View Patent ↗A method of distinguishing a control solution from a sample in an electrochemical test sensor is performed. The method includes adding a control marker to the control solution. The control solution includes the control marker and analyte. The test sensor includes working and counter electrodes, and a reagent. A potential is applied to the test sensor to oxidize the control marker and the analyte. The resulting electrical current is measured. A potential is applied to the test sensor lower than the other potential in which the potential is sufficient to oxidize the analyte and not the control marker. The resulting electrical current is measured. Determining whether a control solution or a sample is present based on the measured electrical currents. To increase the measured current, a salt may be added to the control solution in an amount sufficient to increase the electrical current by at least 5% as compared to a control solution in the absence of a salt.
1. A method of using a control solution and preparing for testing using the same, the method comprising:
providing a control solution, the control solution including a control marker and a predetermined amount of analyte, the control marker being selected from the group consisting of sodium iodide, triethanolamine, tripropanolamine, tributanolamine, xylenol orange, hydroquinone sulfonic acid, cresol red, and salts thereof;
providing an electrochemical test sensor including a first electrode, a second electrode and a reagent; and
introducing the control solution including the control marker and the predetermined amount of analyte to the electrochemical test sensor.
2. The method of claim 1 wherein the analyte is glucose.
3. The method of claim 1 wherein the control marker is sodium iodide.
4. The method of claim 1 wherein the control marker is triethanolamine.
5. The method of claim 1 wherein the control marker is tripropanolamine.
6. The method of claim 1 wherein the control marker is tributanolamine.
7. The method of claim 1 wherein the control marker is xylenol orange.
8. The method of claim 1 wherein the control marker is hydroquinone sulfonic acid or salts thereof.
9. The method of claim 1 wherein the control marker is cresol red.
10. A method of using a control solution and preparing for testing using the same, the method comprising:
providing a control solution, the control solution including a control marker and a predetermined amount of analyte, the control marker being selected from the group consisting of 3-[4-(hydroxyphenyl)amino]-3-oxopropanoic acid, N-acetyl-5-aminosalicyclic acid, N-ethyl-N-(3-sulfopropyl)-3-methylaniline (TOPS), 3-(N-ethyl-3 -methylanilino)-2-hydroxypropanesulfonic acid (TOOS), 8-anilino-1-naphthalenesulfonic acid, 2-napthylamine 1-sulfonic acid, sodium diphenylamine-4-sulfonate, N-ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethylaniline (MAOS), and salts thereof;
providing an electrochemical test sensor including a first electrode, a second electrode and a reagent; and
introducing the control solution including the control marker and the predetermined amount of analyte to the electrochemical test sensor.
11. The method of claim 10 wherein the analyte is glucose.
12. The method of claim 10 wherein the control marker is 3-[4-(hydroxyphenyl)amino]-3-oxopropanoic acid or salts thereof.
13. The method of claim 10 wherein the control marker is N-acetyl-5-aminosalicyclic acid or salts thereof.
14. The method of claim 10 wherein the control marker is N-ethyl-N-(3-sulfopropyl)-3-methylaniline (TOPS) or salts thereof.
15. The method of claim 10 wherein the control marker is 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid (TOOS) or salts thereof.
16. The method of claim 10 wherein the control marker is 8-anilino-1-naphthalenesulfonic acid or salts thereof.
17. The method of claim 10 wherein the control marker is 2-napthylamine 1-sulfonic acid, sodium diphenylamine-4-sulfonate or salts thereof.
18. The method of claim 10 wherein the control marker is sodium diphenylamine-4-sulfonate or salts thereof.
19. The method of claim 10 wherein the control marker is N-ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethylaniline (MAOS) or salts thereof.