Conversion of nitrogen dioxide (NO
View Patent ↗Various systems, devices, NO 2 absorbents, NO 2 scavengers and NO 2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.
1. A system of delivering a therapeutic amount of nitric oxide to a mammal comprising:
a ventilator,
an NO 2 scavenger selected from the group consisting of proline, diphenylamine, a secondary amine and a tertiary amine, and
a receptacle including an inlet, an outlet, and a surface-active material;
wherein the surface-active material includes an absorbent and a reducing agent; and
wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material, such that nitrogen dioxide in the gas flow is converted to nitric oxide.
2. The system of claim 1 , wherein the absorbent is silica gel.
3. The system of claim 1 , wherein the absorbent is activated alumina.
4. The system of claim 1 , further comprising a gas source of nitrogen dioxide, dinitrogen tetraoxide, or nitric oxide.
5. The system of claim 1 , further comprising a gas source of nitric oxide.
6. The system of claim 1 , wherein the receptacle includes the NO 2 scavenger.
7. The system of claim 1 , further comprising a humidified line.
8. The system of claim 7 , wherein the humidified line is heated.
9. The system of claim 7 , wherein the humidified line is heated to about 35° C.