IP Library › Patent Application 14109633
Patent Application
App. No. 14/109,633

FOR INJECTABLE FORMULATIONS CONTAINING ASENAPINE AND METHOD OF TREATMENT USING SAME

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Quick Facts
Patent No.
US None
App. No.
14/109,633
Abstract

The present invention provides a formulation comprising asenapine hemipamoate suspended particles, which formulation can be administered via a Depot provided by an IM injection of the formulation, and which depot does not display a particle-size dependent release rate. The present invention provides also methods of treatment using the same.

Claims (3)

1 - 20 . (canceled)

21 . A pharmaceutical formulation comprising an aqueous suspension of particles of crystalline Form II of asenapine hemipamoate, wherein said asenapine hemipamoate is present at a concentration of 5 wt. % or greater of the suspension, and wherein, said particles comprise less than about 10 vol % of particles having a mean diameter of less than 1 micron and have a d 50 -value of from about 1.5 microns to about 40 microns.

22 . The formulation of claim 21 which is further characterized by providing a consistent release profile of asenapine from a depot injection consistent with that illustrated in FIGS. 9 a to 9 c.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 29, 2014
From: MERCK SHARP & DOHME BV; ORGANON LIMITED
To: FOREST LABORATORIES HOLDINGS LIMITED
Reel/Frame 032077/0550 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 8, 2014
From: MERCK SHARP & DOHME CORP.
To: MERCK SHARP & DOHME B.V.
Reel/Frame 031919/0254 →