IP Library Granted Patent US 9,283,069
Granted Patent B2
US 9,283,069 · App. 14/112,275 · Granted Mar 15, 2016

Intravitreous self adaptive stent

Inventors: David Maxwell Kleinman (Rochester, NY); Trevor John Moody (Seattle, WA); Kenneth Eugene Perry, Jr. (Bainbridge Island, WA)
Assignee: EMPIRE TECHNOLOGY DEVELOPMENT LLC
A61F2/14A61F2/16A61F2/88A61F9/00727A61L31/022A61L31/16A61F2210/0014A61F2230/0071A61F2250/0003
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Quick Facts
Patent No.
US 9,283,069
App. No.
14/112,275
Granted
Mar 15, 2016
Kind
B2
Abstract

An intravitreous stent includes a multi-loop single wire having a proximal end; a distal end; at least a first loop defined by the proximal end and a first portion of the single wire; at least a second loop defined by the distal end and a second portion of the single wire; wherein the first portion is joined to the second portion via a reversing loop portion.

Claims (46)

1. An intravitreous stent comprising:

a multi-loop single wire comprising:

a proximal end;

a distal end;

at least a first loop defined by the proximal end and a first portion of the single wire;

at least a second loop defined by the distal end and a second portion of the single wire, wherein the second loop comprises a sinusoidal wave configured to perpendicularly contact a retina of an eye, such that one or more zenith points or nadir points of the sinusoidal wave are configured to contact the retina;

wherein:

the first portion is joined to the second portion via a reversing loop portion;

the second loop has a diameter that is larger than that of the first loop; and

the intravitreous stent is self adaptive to a dimension of a vitreous cavity in an eye;

and wherein the stent is configured to be straightened prior to or during insertion in the eye.

2. The intravitreous stent of claim 1 , wherein the proximal end, the distal end, or both the proximal end and the distal end comprise a curled feature.

3. The intravitreous stent of claim 1 , wherein the second loop is configured to form to an equator of a vitreous cavity of an eye.

4. The intravitreous stent of claim 1 , wherein the proximal end is configured to reside within the anterior chamber of an eye.

5. The intravitreous stent of claim 1 configured to retain a detached retina in an eye.

6. The intravitreous stent of claim 1 , wherein the single wire comprises a shape memory substance.

7. The intravitreous stent of claim 1 , wherein the single wire comprises a titanium-nickel (Ti-Ni) based alloy.

8. The intravitreous stent of claim 7 , wherein the Ti-Ni based alloy comprises about 43.5 wt % to about 52 wt % Ti and about 48 wt % to about 56.5 wt % Ni.

9. The intravitreous stent of claim 7 , wherein the Ti-Ni based alloy comprises a Ti-Ni-X alloy where X is at least one of Fe, V, Cr, Co, or Nb.

10. The intravitreous stent of claim 9 , wherein the Ti-Ni based alloy comprises about 43.5 wt % to about 51 wt % Ti, about 40 wt % to about 56.5 wt % Ni, and about 0wt % to about 9 wt % X.

11. The intravitreous stent of claim 1 further comprising a fixation point for fixing the stent in an eye.

12. The intravitreous stent of claim 1 further comprising one or more projections for grasping or fixing of the intravitreous stent, wherein the projections comprise one or more regions in the stent configured to receive a suture.

13. The intravitreous stent of claim 1 , further comprising a therapeutic agent.

14. The intravitreous stent of claim 13 , wherein the therapeutic agent is an anti-proliferative drug, a neuron protective drug, an antibiotic, an anti-inflammatory, a glaucoma drug, an anti-viral, or an anti-allergy agent.

15. The intravitreous stent of claim 1 , wherein the proximal end comprises a projection for fixing a natural or synthetic intraocular lens within an eye.

16. A method of treating an ocular disease in a subject, comprising:

implanting an intravitreous stent according to claim 1 in an eye of the subject; wherein: the intravitreous stent is self adaptive to a dimension of a vitreous cavity in the eye, thereby treating the ocular disease in the subject.

17. The method of claim 16 , further comprising suturing the intravitreous stent to scleral tissue at pars plana of a ciliary body in the eye.

18. The method of claim 16 , wherein the ocular disease is vitreoretinopathy.

19. A method for securing a natural or synthetic intraocular lens in an eye, the method comprising:

inserting a cannula through an anterior portion of an eye;

feeding an intravitreous stent through the cannula and into the eye; and

contacting a natural or synthetic intraocular lens with the intravitreous stent to fix a position of the lens within the eye;

wherein: the intravitreous stent comprises:

a multi-loop single wire comprising:

a proximal end;

a distal end;

at least a first loop defined by the proximal end and a first portion of the single wire;

at least a second loop defined by the distal end and a second portion of the single wire, wherein the second loop comprises a sinusoidal wave configured to perpendicularly contact a retina of an eye, such that one or more zenith points or nadir points of the sinusoidal wave are configured to contact the retina; and

wherein:

the first portion is joined to the second portion via a reversing loop portion;

the second loop has a diameter that is larger than that of the first loop; and

the intravitreous stent is self adaptive to a dimension of a vitreous cavity in an eye;

and wherein the stent is configured to be straightened prior to or during insertion in the eye.

20. The method of claim 19 further comprising inserting a natural or synthetic intraocular lens into the eye.

21. The method of claim 19 , wherein the lens is a dislocated natural lens and the intraocular stent fixates the lens from further dislocation.

Assignments (2)
RELEASE OF SECURITY INTEREST IN PATENTS, RECORDED ON JANUARY 29, 2019 AT REEL 048373 FRAME 0217 Recorded Sep 22, 2025
From: CRESTLINE DIRECT FINANCE, L.P., AS COLLATERAL AGENT
To: EMPIRE TECHNOLOGY DEVELOPMENT LLC
Reel/Frame 072936/0464 →
SECURITY INTEREST Recorded Jan 29, 2019
From: EMPIRE TECHNOLOGY DEVELOPMENT LLC
To: CRESTLINE DIRECT FINANCE, L.P.
Reel/Frame 048373/0217 →
Continuity (2)
Provisional Application 61624060 · Apr 13, 2012
Related Publication 20140296976A1 · Oct 2, 2014