Hydrophilic polyurethane foam with low volume swelling
View Patent ↗The invention relates to a specific composition comprising A) isocyanate-functional prepolymers obtainable by reaction of A1) aliphatic diisocyanates with A2) di- to hexa-functional polyalkylene oxides having an ethylene oxide content of 50 to 100 mol %, based on the total amount of the oxyalkylene groups present, B) an aqueous polyurethane suspension, an aqueous polyacrylate suspension or aqueous silica sols, especially for production of hydrophilic, aliphatic polyurethane foams. The invention further provides a process for producing a hydrophilic, aliphatic polyurethane foam, based on the inventive composition, a polyurethane foam obtainable by the process and a wound dressing comprising the polyurethane foam.
1. A composition consisting of
A) an isocyanate-functional prepolymer obtained by reacting
A1) an aliphatic diisocyanate with
A2) a di- to hexafunctional polyalkylene oxide having an ethylene oxide fraction of 50 to 100 mol %, based on the total amount of oxyalkylene groups present, and
B) an aqueous polyurethane suspension,
C) a heterocyclic 4-ring or 6-ring oligomers of low molecular weight aliphatic diisocyanates having a molar mass of 140 to 278 g/mol,
D) optionally C8 to C22 monocarboxylic acids or ammonium or alkali metal salts thereof or C12 to C44 dicarboxylic acids or ammonium or alkali metal salts thereof or alkali metal salts of inorganic acids,
E) a hydrophilic polyisocyanate obtained by reaction of
E1) a low molecular weight aliphatic diisocyanate and/or a polyisocyanate obtained therefrom with an isocyanate functionality of 2 to 6, with
E2) a monofunctional polyalkylene oxide of OH number 10 to 250 and an ethylene oxide fraction of 50 to 100 mol %, based on the total amount of oxyalkylene groups present,
F) optionally a catalyst,
G) optionally a surfactant, and
H) optionally a monohydric or polyhydric alcohol, wherein
the amounts of the components are as follows: 100 parts by weight of prepolymer A), 1 to 60 parts by weight of polymer suspension B), 5-15 parts by weight of oligomers C), and 20 to 80 parts by weight of hydrophilic polyisocyanate E),
and wherein the composition, when prepared as a foam, has a density of from 0.01 to 0.5 g/cm 3 , and a water-extractable fraction of not more than 5 wt %.
2. The composition of claim 1 , wherein the diisocyanate comprises an aliphatic diisocyanate having a molar mass of 140 to 278 g/mol.
3. The composition of claim 1 , wherein the polyalkylene oxide has an OH number of 22.5 to 112.
4. The composition of claim 1 , wherein said aqueous polymer suspension B) is an aqueous, hydrophilicized polyurethane suspension.
5. The composition of claim 1 , wherein said aqueous polymer suspension B) is an aqueous, anionically hydrophilicized polyurethane suspension.
6. The composition of claim 5 , wherein said aqueous, anionically hydrophilicized polyurethane suspension B) is obtained by preparing
J) an isocyanate-functional prepolymer from
J1) an organic polyisocyanate,
J2) a polymeric polyol,
J3) optionally a hydroxyl-functional compound, and
J4) optionally an isocyanate-reactive, an anionic or potentially anionic and/or optionally a nonionic hydrophilicizing agent,
chain extending said isocyanate-functional prepolymer J) by complete or partial reaction of any free NCO groups with
K1) an isocyanate-reactive agent, and/or
K2) optionally an amino-functional compound,
and dispersing said prepolymer J) in water before, during or after said chain-extending reaction, wherein any potentially anionic groups present are converted into the anionic form by partial or complete reaction with a neutralizing agent.
7. A process for producing a hydrophilic aliphatic polyurethane foam, said process comprising producing the composition of claim 1 by mixing the components, foaming the mixture and curing the foamed mixture.
8. A polyurethane foam obtained by the process of claim 7 .
9. A method for treating wound utilizing the polyurethane foam of claim 8 .
10. A wound dressing comprising the polyurethane foam of claim 8 .
11. The wound dressing of claim 10 , comprising a backing layer and/or an adhesive layer and/or a covering layer.
12. The wound dressing of claim 11 , wherein the polyurethane foam is at least regionally connected to the backing layer.
13. The wound dressing of claim 11 , wherein the adhesive layer is at least regionally connected to the polyurethane foam and/or to the polyurethane foam side of the backing layer.
14. The wound dressing of claim 11 , wherein the adhesive layer is at least regionally releasably connected to the covering layer.
15. A polymer system obtained by mixing said components A), B), C) and E) and optionally D), F), G), H) of the composition as claimed in claim 1 .
16. The composition of claim 1 , wherein the aliphatic diisocyanate A1) is hexamethylene diisocyanate, the aqueous polymer suspension B) is an aqueous, hydrophilicized polyurethane suspension, and wherein C) is a heterocyclic 4-ring oligomers.