Stem Cell Mobilization and Tissue Repair and Regeneration
Stem cells are mobilized from bone marrow by administering an amount of Phe-Pro-His-Phe-Asp-Leu-Ser-His-Gly-Ser-Ala-Gin-Val (SEQ ID NO: 1) effective to mobilize the stem cells. This method is useful for promoting preservation, repair, or regeneration of bodily tissue, or revascularization, in a patient in need of such treatment. Alternatively, the mobilized stem cells can be collected for transplant.
1 . A method of mobilizing stem cells from bone marrow of a subject, comprising administering to the subject an amount of (SEQ ID NO: 1) effective to mobilize the stem cells.
2 - 4 . (canceled)
5 . The method of claim 1 , wherein the subject is a human and the amount of (SEQ ID NO: 1) is from about 100 micrograms to about 10 milligrams per administration, administered from 1 time per week to 3 times per day.
6 . A method for treating a subject in need of one or more of preservation, repair, or regeneration of bodily tissue, or revascularization, comprising the method of claim 1 , thereby promoting the one or more of preservation, repair, or regeneration of bodily tissue or regeneration in the subject.
7 . A method for treating a subject in need of one or more of preservation, repair, or regeneration of bodily tissue, or revascularization, comprising the method of claim 5 , thereby promoting the one or more of preservation, repair, or regeneration of bodily tissue or regeneration in the subject.
8 . The method of claim 6 , wherein the tissue that is preserved, repaired or regenerated is pancreatic tissue.
9 . A method of treating diabetes comprising the method of claim 8 .
10 . The method of claim 7 , wherein the tissue that is preserved, repaired or regenerated is pancreatic tissue.
11 . A method for treating diabetes comprising the method of claim 10 .
12 . The method of claim 6 , wherein the tissue that is preserved, repaired, or regenerated is dermal tissue.
13 . A method for treating a dermal wound, comprising the method of claim 12 .
14 . The method of claim 7 , wherein the tissue that is preserved, repaired, or regenerated is dermal tissue.
15 . A method of treating a dermal wound, comprising the method of claim 14 .