IP Library › Granted Patent US 9,243,066
Granted Patent B2
US 9,243,066 · App. 14/126,878 · Granted Jan 26, 2016

Use of M-CSF antibodies in the treatment of osteoarthritis or pain

Inventors: Stefan Steidl (Munich, DE); John Allan Hamilton (Aberfeldie, AU); Andrew David Cook (North Melbourne, AU)
Assignees: University of Melbourne; Morpho Sys AG
C07K16/2866C07K16/243C07K16/244C07K16/249A61K2039/505C07K2317/76
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Quick Facts
Patent No.
US 9,243,066
App. No.
14/126,878
Granted
Jan 26, 2016
Kind
B2
Abstract

The present invention relates generally to a method for the treatment and/or prophylaxis of osteoarthritis (OA) and/or pain. In accordance with the present invention, an antagonist of c-Fms is effective in the treatment of osteoarthritis and/or pain. An antagonist of M-CSF includes, but is not limited to, an antibody that is specific for M-CSF, IL-34 or c-Fms.

Claims (4)

1. A method for the treatment of pain in a subject, comprising administering to the subject an antibody or antigen binding fragment thereof specific for M-CSF, wherein the pain is post-surgical pain or bone cancer pain.

2. The method of claim 1 , wherein said pain is post-surgical pain.

3. The method of claim 1 , wherein said pain is bone cancer pain.

4. The method claim 1 , wherein said subject is a human.

Assignments (3)
CHANGE OF NAME Recorded May 1, 2025
From: MORPHOSYS AG
To: MORPHOSYS GMBH
Reel/Frame 071149/0626 →
EXCERPT OF COMMERCIAL REGISTER REFLECTING NEW ADDRESS Recorded Apr 28, 2017
From: MORPHOSYS AG
To: MORPHOSYS AG
Reel/Frame 042357/0552 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 17, 2013
From: HAMILTON, JOHN ALLAN, DR; COOK, ANDREW DAVID, DR; STEIDL, STEFAN, DR
To: MORPHOSYS AG
Reel/Frame 031796/0272 →
Priority Claims (1)
EP 11174305 · Jul 18, 2011 · regional
Continuity (2)
Provisional Application 61508717 · Jul 18, 2011
Related Publication 20140205608A1 · Jul 24, 2014