Endoluminal prosthesis

1. An endoluminal prosthesis comprising:

a tubular main body comprising a proximal end opening, a distal end opening, a lumen extending between the proximal end opening and the distal end opening, a sidewall, and a fenestration in the sidewall;

a branch disposed external of the main body and comprising a tubular retrograde branch segment, a tubular antegrade branch segment, and a tubular branch junction, the retrograde branch segment comprising an inlet opening fluidly coupled to the fenestration of the main body and an outlet opening fluidly coupled to the branch junction, the outlet opening of the retrograde branch segment positioned longitudinally between the proximal end opening and the fenestration of the main body, the antegrade branch segment comprising an inlet opening fluidly coupled to the branch junction and an outlet opening positioned longitudinally distal of the inlet opening of the antegrade branch segment, the retrograde branch segment and the antegrade branch segment in fluid communication with one another through the branch junction.

2. The prosthesis of claim 1 , wherein the fenestration of the main body comprises a first fenestration and a second fenestration positioned distal of the first fenestration, the inlet opening of the retrograde branch segment is fluidly coupled to the second fenestration, and the branch junction comprises a cannulation opening fluidly coupled to the first fenestration.

3. The prosthesis of claim 2 , wherein the outlet opening of the antegrade branch segment is positioned longitudinally between the first fenestration and the second fenestration.

4. The prosthesis of claim 2 , wherein the branch junction comprises an inlet opening fluidly coupled to the outlet opening of the retrograde branchsegment, and an outlet opening fluidly coupled to the inlet opening of the antegrade branch segment.

5. The prosthesis of claim 4 , wherein the branch junction comprises a sidewall, the cannulation opening of the branch junction comprises a first end opening, the outlet opening of the branch junction comprises a second end opening, and the inlet opening of the branch junction comprises a fenestration in the sidewall of the branch junction.

6. The prosthesis of claim 4 , wherein the branch junction comprises a sidewall, the inlet opening of the branch junction comprises a first end opening, the outlet opening of the branch junction comprises a second end opening, and the cannulation opening of the branch junction comprises a fenestration in the sidewall of the branch junction.

7. The prosthesis of claim 6 , wherein the branch comprises a U-shaped tubular member, the branch junction comprises a curved portion of the U-shaped tubular member, and each of the retrograde branch segment and the antegrade branch segment comprises a leg portion of the U-shaped tubular member.

8. The prosthesis of claim 7 , wherein the first end opening and the second end opening of the branch junction are disposed adjacent to one another and distal of the first fenestration of the main body.

9. The prosthesis of claim 2 , wherein the branch junction comprises a shunt fluidly coupled to the first fenestration of the main body.

10. The prosthesis of claim 1 , further comprising a support structure attached to the sidewall of the main body.

11. The prosthesis of claim 1 , wherein each of the branch junction, the retrograde branch segment, and the antegrade branch segment comprises a sidewall and a support structure attached to the sidewall.

12. The prosthesis of claim 1 , wherein the retrograde branch segment and the antegrade branch segment are aligned with one another relative to a circumference of the main body and arranged in a stacked configuration in which the retrograde branch segment is positioned radially between the antegrade branch segment and the main body.

13. The prosthesis of claim 1 , wherein the retrograde branch segment and the antegrade branch segment are misaligned with one another relative to a circumference of the main body and arranged in a side-by-side configuration in which the retrograde branch segment is positioned adjacent to the antegrade branch segment and each of the retrograde branch segment and the antegrade branch segment is positioned adjacent to the main body.

14. The prosthesis of claim 1 , wherein the retrograde branch segment extends in a retrograde direction from the fenestration of the main body to the branch junction, and the antegrade branch segment extends in an antegrade direction from the branch junction.

15. A method of deploying an endoluminal prosthesis, the method comprising:

introducing a delivery device through a first fenestration in a sidewall of a main body of the prosthesis and into a branch junction of the prosthesis;

advancing the delivery device through the branch junction into an antegrade branch segment fluidly coupled to the branch junction;

deploying a branch extension prosthesis within the antegrade branch segment with the delivery device;

deploying an extension prosthesis within the main body of the prosthesis, a distal end of the extension prosthesis being disposed longitudinally between the first fenestration and a second fenestration in the sidewall of the main body;

wherein the prosthesis comprises a retrograde branch segment fluidly coupled to each of the second fenestration and the branch junction, and the extension prosthesis seals the first fenestration.