Methods and devices for treating tissue
View Patent ↗The invention provides a system and method for achieving the cosmetically beneficial effects of shrinking collagen tissue in the dermis or other areas of tissue in an effective, non-invasive manner using an array of electrodes. Systems described herein allow for improved treatment of tissue. Additional variations of the system include array of electrodes configured to minimize the energy required to produce the desired effect.
1. A method for treating tissue by applying energy to a region of the tissue, the method comprising:
maintaining a cooling surface at a temperature that cools tissue when heated;
placing the cooling surface against a tissue surface above the region of the tissue to which energy is applied;
advancing a plurality of electrodes into the tissue at a second tissue surface spaced from the tissue surface placed against the cooling surface and at an angle relative to the tissue surface placed against the cooling surface, each electrode including an active region at a distal portion thereof, such that the active region is directly below the tissue placed against the cooling surface to allow for direct cooling of a tissue region above the active region of the electrodes; and
applying energy to the active region of the electrodes to cause a change in the region of the tissue to which energy is applied.
2. The method of claim 1 , further comprising monitoring the cooling surface for an increase in temperature.
3. The method of claim 1 , where advancing the plurality of electrodes comprises first applying an impact force to the electrodes such that the electrodes penetrate the tissue and subsequently, advancing the electrodes further into the tissue.
4. The method of claim 1 , further comprising:
placing a portion of the second surface of the tissue that is adjacent to each electrode in a state of traction as the electrodes are inserted into the tissue; and
advancing at least one of the electrodes through the second tissue surface.
5. The method of claim 1 , where each electrode extends through an opening in an introducer member, where pressing the introducer member against the second tissue surface places the second tissue surface in fraction.
6. The method of claim 1 , further comprising placing a thermoelectric cooling device in contact with the cooling surface.
7. The method of claim 1 , further comprising delivering a fluid through the cooling surface.
8. The method of claim 1 , where the region of tissue comprises tissue selected from the group consisting of the dermis, a tumor, and a blood vessel.
9. The method of claim 1 , where the cooling surface is visually transparent.
10. The method of claim 1 , where the cooling surface is visually translucent.
11. The method of claim 1 , further comprising marking the tissue surface using the cooling surface or one of the plurality of electrodes.
12. The method of claim 11 , where marking the tissue surface comprises marking the tissue surface with an ink or dye.
13. The method of claim 12 , where the ink or dye is not visible unless illuminated by a light source.
14. The method of claim 1 , where the electrodes enter the second tissue surface at a location that is spaced from the cooling surface to allow for direct cooling of the entire tissue region above the active region without having to cool the entry location.
15. The method of claim 1 , where applying energy to the active region of the electrodes to a region of tissue beneath the tissue surface causes a temperature increase in a dermis region to about 65 degrees Celsius.
16. A method for applying energy to a region of tissue, the method comprising:
advancing a plurality of electrodes at an angle relative to a tissue surface into the tissue, each electrode including an active region at a distal portion thereof;
maintaining a cooling surface at a temperature that cools tissue when heated;
placing the cooling surface against the tissue surface, where the cooling surface is maintained a temperature and where the active region of the electrode is directly below the cooling surface and where the entry of the electrodes at the tissue surface is at an entry location that is spaced from the cooling surface to allow for direct cooling of an entire tissue region above the active region, where the electrodes do not pass through the cooling surface when inserted into the tissue surface; and
applying energy to the active region of the electrodes to a region of tissue beneath the tissue surface to cause a change in the region of tissue.
17. The method of claim 16 , further comprising monitoring the cooling surface for an increase in temperature.
18. The method of claim 16 , where advancing the plurality of electrodes comprises first applying an impact force to the electrodes such that the electrodes penetrate the tissue and subsequently, advancing the electrodes further into the tissue.
19. The method of claim 16 , further comprising:
placing a portion of the surface of the tissue that is adjacent to each electrode in a state of traction as the electrodes are inserted into the tissue; and
advancing at least one of the electrodes through the tissue surface.
20. The method of claim 16 , where each electrode extends through an opening in an introducer member, where pressing the introducer member against the tissue surface places the tissue surface in fraction.
21. The method of claim 16 , further comprising activating a power supply to energize adjacent electrodes at different times.
22. The method of claim 16 , further comprising placing a thermoelectric cooling device in contact with the cooling surface.
23. The method of claim 16 , further comprising delivering a fluid through the cooling surface.
24. The method of claim 16 , where the region of tissue comprises tissue selected from the group consisting of the dermis, a tumor, and a blood vessel.
25. The method of claim 16 , where the cooling surface is visually transparent.
26. The method of claim 16 , where the cooling surface is visually translucent.
27. The method of claim 16 , further comprising marking the tissue surface using the cooling surface or one of the plurality of electrodes.
28. The method of claim 27 , where marking the tissue surface comprises marking the tissue surface with an ink or dye.
29. The method of claim 28 , where the ink or dye is not visible unless illuminated by a light source.
30. The method of claim 16 , where the electrodes enter the tissue surface at the location that is spaced from the cooling surface to allow for direct cooling of the entire tissue region above the active region without having to cool the entry location.
31. The method of claim 16 , where applying energy to the active region of the electrodes to a region of tissue beneath the tissue surface causes a temperature increase in a dermis region to about 65 degrees Celsius.
32. A method for treating a target region of a tissue with an apparatus, the method comprising the actions of:
placing a cooling surface of an apparatus against a first tissue surface of a tissue to be treated, wherein the first tissue surface is located above a target region;
advancing a plurality of electrodes such that the plurality of electrodes penetrate through a second tissue surface and into the target region, wherein second tissue surface is proximate to the first tissue surface and wherein the plurality of electrodes advances at an angle relative to the second tissue surface such that an active region located at a distal portion of each of the plurality of electrodes is advanced into the target region;
applying energy to the active region of the plurality of electrodes;
monitoring a tissue surface temperature of the first tissue surface; and
adjusting a temperature of the cooling surface to maintain the tissue surface temperature of the first tissue surface within a desired temperature range, whereby the apparatus provides a cooling of the tissue proximate to the active region of the electrodes.