Microwell plate
View Patent ↗A microwell plate is described, including a frame 2 that has a frame plate 4 made of a first material having holes 2 ′, and a vessel 3 formlockingly connected to the frame plate 4 and made from a poly(aliphatic ester)-polycarbonate including soft block ester units, derived from monomers including an alpha, omega C 6-20 aliphatic dicarboxylic acid or derivative thereof, a dihydroxyaromatic compound, and a carbonate source.
1. A microwell plate comprising:
a frame ( 2 ) comprising
a frame plate ( 4 ) made of a first material having holes ( 2 ′), and
a vessel ( 3 ) formlockingly connected to the frame plate 4 and made from a poly(aliphatic ester)-polycarbonate comprising soft block ester units, derived from monomers comprising:
an alpha, omega C 6-20 aliphatic dicarboxylic acid or derivative thereof,
a dihydroxyaromatic compound, and
a carbonate source,
wherein the vessel has a wall thickness of less than or equal to 1 mm.
2. The microwell plate of claim 1 , wherein the alpha, omega C 6-20 aliphatic dicarboxylic acid or derivative thereof comprises sebacic acid.
3. The microwell plate of claim 1 , wherein the poly(aliphatic ester)-polycarbonate is of the formula (6b)
wherein m is 4 to 18, x and y each represent average weight percentages of the poly(aliphatic ester)-polycarbonate wherein the average weight percentage ratio x:y is 10:90 to 1:99, wherein x+y is 100, and each R 3 is independently derived from a dihydroxyaromatic compound of formula (3)
wherein Ra and Rb are each independently a halogen, C1-12 alkoxy, or C1-12 alkyl; Xa is a single bond, —O—, —S—, —S(O)—, S(O) 2 —, —C(O)—, or a C 1-18 organic group; and p and q are each independently integers of 0 to 4 or formula (5)
wherein each R h is independently a halogen atom, a C 1-10 hydrocarbyl such as a C 1-10 alkyl group, a halogen-substituted C 1-10 alkyl group, a C 6-10 aryl group, or a halogen-substituted C 6-10 aryl group, and n is 0 to 4.
4. The microwell plate of claim 3 , wherein the poly(aliphatic ester)-polycarbonate is of formula (6c)
wherein m is 4 to 18 and wherein the average weight percentage ratio x:y is 10:90 to 1:99, wherein x+y is 100.
5. The microwell plate of claim 3 , wherein m is 8.
6. The microwell plate of claim 1 , wherein the poly(aliphatic ester)-polycarbonate has an MFR of 66 to 150 g/10 min at 300° C. and under a load of 1.2 kilograms according to ASTM D1238-10.
7. The microwell plate of claim 1 , wherein the poly(aliphatic ester)-polycarbonate has an HDT is 80 to 140° C. at 0.45 mega Pascal (MPa) using unannealed 3.2 mm plaques according to ASTM D648-07.
8. The microwell plate of claim 7 , wherein the poly(aliphatic ester)-polycarbonate has a Notched Izod Impact (NII) ductility of 30 to 100%, using ⅛-inch thick bars (3.18 mm) at 23° C. according to ASTM D256-10.
9. The microwell plate of claim 1 , wherein the poly(aliphatic ester)-polycarbonate has an HDT is 80 to 140° C. at 1.82 mega Pascal (MPa) using unannealed 3.2 mm plaques according to ASTM D648-07.
10. The microwell plate of claim 9 , wherein the polu(aliphatic ester)-polycarbonate has a Notched Izod Impact (NII) ductility of 30 to 100%, using ⅛-inch thick bars (3.18 mm) at 23° C. according to ASTM D256-10.
11. The microwell plate of claim 1 , wherein the poly(aliphatic ester)-polycarbonate has a Notched Izod Impact (NII) ductility of 30 to 100%, using ⅛-inch thick bars (3.18 mm) at 23° C. according to with ASTM D256-10.
12. The microwell plate of claim 1 , wherein the thermoplastic composition has a Notched Izod Impact (NII) of 400 to 700 Joules per meter (Jim) using ⅛-inch thick bars (3.18 mm) at 23° C. according to with ASTM D256-10.
13. The microwell plate of claim 1 , wherein the poly(aliphatic ester)-polycarbonate is derived from monomers consisting essentially of
the alpha, omega C 6-20 aliphatic dicarboxylic acid or derivative thereof,
the dihydroxyaromatic compound, and
the carbonate source.
14. The microwell plate of claim 1 , comprising a plurality of said vessels.
15. The microwell plate of claim 1 , wherein the vessel ( 3 ) has a wall thickness of 0.005 to 1 mm.
16. The microwell plate of claim 1 , wherein the vessel ( 3 ) has a wall thickness of 0.01 to 0.5 mm.
17. The microwell plate of claim 1 , wherein the vessel ( 3 ) has a wall thickness of 0.05 to 0.2 mm.
18. The microwell plate of claim 1 , wherein the vessel ( 3 ) has a collar ( 12 ) having two projections ( 13 , 14 ) thereon that respectively engage an upper surface ( 7 ) and the underside ( 8 ) of the plate ( 4 ).