IP Library Granted Patent US 8,813,625
Granted Patent B1
US 8,813,625 · App. 14/167,204 · Granted Aug 26, 2014

Methods of manufacturing variable porosity flow diverting devices

Inventors: Vallabh Janardhan (Dallas, TX); Vikram Janardhan (Sacramento, CA)
Assignee: Insera Therapeutics, Inc.
A61B17/22032D04C1/06
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Quick Facts
Patent No.
US 8,813,625
App. No.
14/167,204
Granted
Aug 26, 2014
Kind
B1
Abstract

Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Claims (60)

1. A method of manufacturing a device for treating a vascular cavity, the method comprising:

arranging a plurality of spools on a yarn wheel, each of the spools comprising wire;

braiding the wire from each of the plurality of spools to form a textile structure, wherein braiding the wire comprises:

braiding the wire for a first duration to form a first segment of the textile structure,

wherein the first duration comprises:

a third duration, and

a fourth duration after the third duration,

wherein braiding the wire during the first duration comprises:

rotating the yarn wheel 180° at a first speed during the third duration,

rotating the yarn wheel 180° at a second speed different than the first speed during the fourth duration, and

pulling a puller at a third speed, at least one of the first speed and the second speed being greater than the third speed, and

braiding the wire for a second duration to form a second segment of the textile structure,

wherein the second duration comprises:

a fifth duration, and

a sixth duration after the fifth duration,

wherein braiding the wire during the second duration comprises:

rotating the yarn wheel 180° at a fourth speed during the fifth duration,

rotating the yarn wheel 180° at a fifth speed different than the fourth speed during the sixth duration, and

pulling the puller at a sixth speed, at least one of the fourth speed and the fifth speed less than the sixth speed; and

heat treating the textile structure, wherein after the heat treatment the textile structure is expandable from a compressed state to an expanded state, the textile structure comprising a bulb in the expanded state.

2. The method of claim 1 , wherein the first duration is before the second duration.

3. The method of claim 1 , wherein the first duration is after the second duration.

4. The method of claim 1 , wherein the first segment comprises the bulb.

5. The method of claim 1 , wherein the second segment comprises the bulb.

6. The method of claim 1 , further comprising a second bulb, wherein the first segment comprises the bulb and the second segment comprises the second bulb.

7. The method of claim 1 , wherein braiding the textile structure is around a first mandrel, the method further comprising a first preliminary heat treatment before the heat treatment, wherein the heat treatment is on a second mandrel different than the first mandrel, wherein the second mandrel comprises a shape of the bulb.

8. The method of claim 1 , wherein braiding the textile structure is around a mandrel comprising a shape of the bulb, and wherein the heat treatment is on the mandrel.

9. The method of claim 1 , further comprising coating a portion of the bulb with a polymer.

10. A method of manufacturing a device for treating a vascular cavity, the method comprising:

braiding a plurality of wires to form a textile structure, each of the plurality of wires extending from one of a plurality of spools on a yarn wheel,

wherein braiding the wires comprises:

braiding the wires for a first duration to form a first segment of the textile structure,

wherein the first duration comprises:

a second duration, and

a third duration after the second duration,

wherein braiding the wires during the first duration comprises:

rotating the yarn wheel 180° at a first speed during the second duration,

rotating the yarn wheel 180° at a second speed different than the first speed during the third duration, and

pulling a puller at a third speed, and

heat treating the textile structure to impart an expanded shape comprising a bulb.

11. The method of claim 10 , wherein at least one of the first speed and the second speed is greater than the third speed.

12. The method of claim 10 , wherein braiding the wires further comprises:

braiding the wires for a fourth duration to form a second segment of the textile structure.

13. The method of claim 12 , wherein the first duration is before the fourth duration.

14. The method of claim 12 , wherein the first duration is after the fourth duration.

15. The method of claim 12 , wherein a plurality of bulbs comprises the bulb, and wherein the first segment comprises a first bulb of the plurality of bulbs and the second segment comprises a second bulb of the plurality of bulbs.

16. A method of manufacturing a device for treating a vascular cavity, the method comprising:

braiding a plurality of wires to form a textile structure comprising a bulb,

each of the wires on a spool,

the spools arranged on a yarn wheel,

wherein after braiding the plurality of wires the textile structure has a longitudinal axis and comprises:

a first longitudinal segment having a length along the longitudinal axis and a circumference around the longitudinal axis, the first longitudinal segment comprising:

a first circumferential portion extending along the entire length and around a first part of the circumference on a first side of the longitudinal axis, the first circumferential portion having a braid angle between 91° and 180°, and

a second circumferential portion extending along the same entire length and around a second part of the circumference along a second side of the longitudinal axis different than the first side, the second circumferential portion having a braid angle between 0° and 90°.

17. The method of claim 16 , wherein braiding the plurality of wires comprises:

rotating the yarn wheel 180° at a first speed during a first duration, and

rotating the yarn wheel 180° at a second speed different than the first speed during a second duration different than the first duration.

18. The method of claim 16 , wherein after braiding the plurality of wires the textile structure further comprises a second longitudinal segment along the longitudinal axis adjacent to the first longitudinal segment, the second longitudinal segment having a braid angle between 0° and 90°.

19. The method of claim 18 , wherein after braiding the plurality of wires the textile structure further comprises a third longitudinal segment along the longitudinal axis adjacent to the first longitudinal segment, the third longitudinal segment having a braid angle between 0° and 90°, wherein the first longitudinal segment comprises the bulb, wherein the bulb is elongate, wherein the second longitudinal segment comprises a second bulb, wherein the second bulb is spherical, wherein the third longitudinal segment comprises a third bulb, and wherein the third bulb is spherical.

20. The method of claim 16 , wherein the first circumferential portion has a porosity between 60% and 78%.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Sep 9, 2021
From: KNOBBE, MARTENS, OLSON & BEAR, LLP
To: INSERA THERAPEUTICS, INC.
Reel/Frame 057454/0677 →
SECURITY INTEREST Recorded Jun 30, 2020
From: INSERA THERAPEUTICS, INC.
To: KNOBBE, MARTENS, OLSON & BEAR, LLP
Reel/Frame 053095/0350 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 29, 2014
From: JANARDHAN, VALLABH; JANARDHAN, VIKRAM
To: INSERA THERAPEUTICS, INC.
Reel/Frame 032082/0944 →
Continuity (1)
Continuation 13953540 · Jul 29, 2013