Devices, compositions and methods for bone and tissue augmentation

1. A structural alloplastic bone graft composition for augmentation, repair and/or fusion of bone, comprising:

(i) a biodegradable side chain crystallizable polymer having a first order transition above the body temperature of a patient, the biodegradable side chain crystallizable polymer having a flowable property at a delivery temperature above the transition temperature, the delivery temperature sufficiently low to avoid damage to tissue adjacent a delivery site with the patient's body;

(ii) an osteoconductive material; and

(iii) an osteoinductive material,

wherein the side chain crystallizable polymer comprises an amount of polar groups selected to increase the adhesion of the side chain crystallizable polymer to a bone tissue.

2. The structural alloplastic bone graft composition of claim 1 , wherein the biodegradable side chain crystallizable polymer comprises a —(CH 2 )n- group in a side chain, where n is an integer in the range of about 6 to about 30.

3. The structural alloplastic bone graft composition of claim 2 , where n is an integer in the range of about 20 to about 30.

4. The structural alloplastic bone graft composition of claim 1 , wherein the biodegradable side chain crystallizable polymer is a copolymer comprising at least a first recurring unit having an optional —(CH 2 )m- group where m is an integer in the range of about 0 to about 5; and at least a second recurring unit having a —(CH 2 )n- group where n is an integer in the range of about 6 to about 30.

5. The structural alloplastic bone graft composition of claim 4 , wherein at least one of the recurring units is an alkyl methacrylate.

6. The structural alloplastic bone graft composition of claim 4 , wherein the copolymer comprises two or more recurring units selected from the group consisting of methyl methacrylate, ethyl methacrylate, hexyl methacrylate, and behenyl methacrylate.

7. The structural alloplastic bone graft composition of claim 1 , wherein

(i) the polymer has a solid state when within a first temperature range, the first temperature range selected to substantially correspond to temperatures generally found in anatomical bone structures of living mammals, the solid state having mechanical properties suitable for supporting and/or augmenting bone tissue;

(ii) the polymer has a second transition temperature range, the second transition temperature range being above the first temperature range;

(iii) the polymer has an extrudable fluid state when in a third temperature range, the third temperature range being above the second temperature range; the third temperature range selected to correspond to therapeutically acceptable temperatures for the bone tissue being treated, and

(iv) when the polymer is in the extrudable fluid state in the third temperature range, the composition has a viscosity sufficiently low to permit injection into the bone tissue being treated.

8. The structural alloplastic bone graft composition of claim 7 , wherein the first temperature range is from about 37° C. to about 41° C.

9. The structural alloplastic bone graft composition of claim 7 , wherein the third temperature range is from about 45° C. to about 100° C.

10. The structural alloplastic bone graft composition of claim 9 , wherein the third temperature range is from about 50° C. to about 80° C.

11. The structural alloplastic bone graft composition of claim 1 , further comprising a radio-opaque additive.