Obstructive sleep apnea treatment devices, systems and methods

1. A method of treating a patient, comprising:

sensing a biological parameter indicative of respiration;

analyzing the biological parameter to identify a respiratory cycle;

identifying an inspiratory phase of the respiratory cycle; and

determining a start time for delivery of a stimulation to a hypoglossal nerve of the patient by identifying a duration of the inspiratory phase of the respiratory cycle that is greater than a predetermined portion of a duration of an entirety of the respiratory cycle.

2. The method of claim 1 , wherein sensing the biological parameter includes sensing at least one of impedance, airflow, movement, and pressure, by a sensing device.

3. The method of claim 1 , wherein analyzing the biological parameter to identify the respiratory cycle includes identifying biological parameter peaks with a processor, the processor being operatively coupled to the sensing device.

4. The method of claim 3 , further comprising:

comparing amplitudes of the biological parameter peaks to a threshold amplitude.

5. The method of claim 1 , wherein determining the start time for delivery of the stimulation includes processing the biological parameter with a processor.

6. The method of claim 5 , further comprising:

delivering the stimulation to the hypoglossal nerve of the patient with a stimulation device operatively coupled to the processor.

7. The method of claim 1 , wherein identifying the inspiratory phase of the respiratory cycle includes identifying a biological parameter peak and a preceding biological parameter negative peak, and wherein a portion of the respiratory cycle between the biological parameter peak and the preceding biological parameter negative peak is the inspiratory phase.

8. The method of claim 7 , wherein identifying the biological parameter peak and the preceding biological parameter negative peak includes processing the biological parameter with a processor operatively coupled to the sensing device.

9. The method of claim 1 , wherein the biological parameter is indicative of a respiratory waveform.

10. The method of claim 9 , wherein analyzing the biological parameter to identify the respiratory cycle includes identifying peaks of the respiratory waveform.

11. A method of treating a patient, comprising:

monitoring a signal relating to a biological parameter indicative of respiration from a sensing device;

evaluating the signal to identify a respiratory cycle;

identifying an inspiratory phase of the respiratory cycle; and

identifying a start time for delivery of a stimulation to a hypoglossal nerve of the patient, wherein identifying the start time includes comparing the inspiratory phase to the respiratory cycle and further includes determining that a duration of the inspiratory phase is greater than a predetermined portion of a duration of an entirety of the respiratory cycle.

12. The method of claim 11 , wherein the biological parameter includes at least one of impedance, airflow, movement, and pressure sensed with the sensing device, and wherein identifying the start time for delivery of the stimulation includes processing the sensed biological parameter with a processor operatively coupled to the sensing device.

13. The method of claim 12 , further comprising:

delivering the stimulation to the hypoglossal nerve of the patient with a stimulation device operatively coupled to the processor.

14. The method of claim 11 , wherein evaluating the signal includes identifying peaks of a respiratory waveform, wherein the peaks are indicative of the respiratory cycle.

15. The method of claim 14 , further comprising:

comparing amplitudes of the peaks to a threshold amplitude.

16. The method of claim 11 , further comprising:

comparing a duration of a portion of the inspiratory phase to the duration of the entirety of the respiratory cycle.

17. A method of treating a patient, comprising:

observing a signal indicative of a biological parameter from a sensing device to identify a respiration waveform;

identifying a respiratory cycle of the respiration waveform;

identifying an inspiratory phase of the respiratory cycle; and

setting a start time for delivery of a stimulation to a hypoglossal nerve of the patient by comparing the inspiratory phase to the respiratory cycle and by determining that a duration of a portion of the inspiratory phase is greater than a predetermined portion of a duration of an entirety of the respiratory cycle.

18. The method of claim 17 , wherein comparing the inspiratory phase to the respiratory cycle includes comparing the duration of the portion of the inspiratory phase to the predetermined portion of the duration of the entirety of the respiratory cycle with a processor operatively coupled to the sensing device.

19. The method of claim 18 , further comprising:

delivering the stimulation to the hypoglossal nerve of the patient with a stimulation device operatively coupled to the processor.