Method for treating a pulmonary hypertension condition
View Patent ↗A method for treating a pulmonary hypertension condition such as pulmonary arterial hypertension (PAH) in a subject comprises administering to the subject a therapeutically effective amount of ambrisentan, wherein, at baseline, time from first diagnosis of the condition in the subject is not greater than about 2 years.
1. A method for treating a pulmonary hypertension condition in a human patient, comprising administering to the patient a therapeutically effective amount of ambrisentan and a therapeutically effective amount of an agent selected from the group consisting of sildenafil, tadalafil and vardenafil.
2. The method of claim 1 , wherein the pulmonary hypertension condition is pulmonary arterial hypertension (PAH).
3. The method of claim 2 , wherein the PAH is of WHO Class II, III or IV.
4. The method of claim 1 , wherein the agent is tadalafil.
5. The method of claim 1 , wherein the ambrisentan is administered in a daily dosage amount of about 1 mg to about 25 mg.
6. The method of claim 1 , wherein the ambrisentan is administered in a daily dosage amount of about 2.5 mg to about 10 mg.
7. The method of claim 1 , wherein the ambrisentan and the agent are administered in one dosage form for administration at the same time.
8. The method of claim 1 , wherein the ambrisentan and the agent are administered separately at different times.
9. A method for treating pulmonary arterial hypertension (PAH) in a human patient, comprising administering to the patient a therapeutically effective amount of ambrisentan and a therapeutically effective amount of tadalafil.
10. The method of claim 9 , wherein the PAH is idiopathic PAH.
11. The method of claim 9 , wherein the PAH is of WHO Class II, III or IV.
12. The method of claim 9 , wherein the ambrisentan is administered in a daily dosage amount of about 1 mg to about 25 mg.
13. The method of claim 9 , wherein the ambrisentan is administered in a daily dosage amount of about 2.5 mg to about 10 mg.
14. The method of claim 13 , wherein the ambrisentan and the tadalafil are administered in one dosage form for administration at the same time.
15. The method of claim 13 , wherein the ambrisentan and the tadalafil are administered separately at different times.