NECKLACE-SHAPED PHYSIOLOGICAL MONITOR
The invention provides a neck-worn sensor (referred to herein as the ‘necklace’) that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate the patient's pulse pressure. And from pulse pressure and pulse transit time, a second algorithm, also employing a linear algorithm, can estimate systolic blood pressure and diastolic blood pressure. Thus, the necklace can measure all five vital signs along with hemodynamic parameters. It also includes a motion-detecting accelerometer, from which it can determine motion-related parameters such as posture, degree of motion, activity level, respiratory-induced heaving of the chest, and falls.
1 . A system for measuring pulse transit time (PTT) and configured to be worn around a patient's neck, comprising:
an ECG system comprising an analog ECG circuit in electrical contact with at least two ECG electrodes, the ECG system configured to generate an analog ECG waveform;
an impedance system comprising an analog impedance circuit in electrical contact with at least two impedance electrodes, the impedance system configured to generate an analog impedance waveform;
a digital processing system comprising a microprocessor and an analog-to-digital converter and configured to receive the analog ECG and impedance waveforms, the analog-to-digital converter configured to digitize the analog ECG waveform to generate a digital ECG waveform and digitize the analog impedance waveform to generate a digital impedance waveform, and the microprocessor configured to process the digital ECG waveform to determine a first time point, process the digital impedance waveform to determine a second time point, and analyze the first and second time points to determine PTT; and,
a cable configured to be worn around the patient's neck, the cable housing the analog ECG circuit, the analog impedance circuit, and the digital processing system.
2 . The system of claim 1 , wherein the cable further comprises a plurality of wires that connect the ECG system to the digital processing system, and the impedance system to the digital processing system.
3 . The system of claim 1 , wherein the cable comprises a flexible circuit that connects the ECG system to the digital processing system.
4 . The system of claim 1 , wherein the cable comprises a flexible circuit that connects the impedance system to the digital processing system.
5 . The system of claim 1 , wherein the cable comprises at least two non-flexible circuit boards connected to each other with a flexible conductor.
6 . The system of claim 5 , wherein the flexible conductor is a flexible circuit.
7 . The system of claim 5 , wherein the flexible conductor is a plurality of wires.
8 . The system of claim 5 , wherein one of the non-flexible circuit boards comprises the ECG system, and the other comprises the digital processing system.
9 . The system of claim 5 , wherein one of the non-flexible circuit boards comprises the impedance system, and the other comprises the digital processing system.
10 . The system of claim 1 , wherein the cable comprises a first ECG electrode in a first segment configured to contact a first side of the patient's chest, and a second ECG electrode in a second segment configured to contact a second, opposing side of the patient's chest.
11 . The system of claim 1 , wherein the cable comprises a first impedance electrode in a first segment configured to contact a first side of the patient's chest, and a second impedance electrode in a second segment configured to contact a second, opposing side of the patient's chest.
12 . The system of claim 1 , wherein the cable comprises a first segment comprising a first ECG electrode and a first impedance electrode, the first segment configured to contact a first portion of the patient's chest, and a second segment comprising a second ECG electrode and a second impedance electrode, the second segment configured to contact a second, opposing segment of the patient's chest.
13 . The system of claim 1 , wherein the impedance system comprises four distinct electrodes.
14 . The system of claim 13 , wherein the impedance system comprises a first current-injecting electrode, a second current-injecting electrode, a first voltage-measuring electrode, and a second voltage-measuring electrode.
15 . The system of claim 14 , wherein the cable comprises a first segment comprising a first ECG electrode, the first current-injecting electrode, and the first voltage-measuring electrode, the first segment configured to contact a first portion of the patient's chest, and a second segment comprising a second ECG electrode, the second current-injecting electrode, and the second voltage-measuring electrode, the second segment configured to contact a second, opposing segment of the patient's chest.
16 . The system of claim 1 , further comprising a battery system configured to power the ECG system, the impedance system, and the digital processing system.
17 . The system of claim 16 , wherein the cable comprises the battery system.
18 . The system of claim 17 , wherein the cable comprises a first connector and the battery system comprises a second connector, with the first connector mated to the second connector so that the battery system can be detachably removed.
19 . The system of claim 1 , further comprising a wireless transceiver.
20 . The system of claim 19 , wherein the cable houses the wireless transceiver.
21 . The system of claim 20 , wherein the wireless transceiver is one of a Bluetooth transceiver and an 802.11-based transceiver.
22 . The system of claim 1 , further comprising a USB connector in electrical contact with a flash memory system.
23 . The system of claim 22 , wherein the cable comprises the USB connector.