IP Library › Granted Patent US 9,034,825
Granted Patent B2
US 9,034,825 · App. 14/186,331 · Granted May 19, 2015

Treatment of myocardial injury with humanin analogs

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Quick Facts
Patent No.
US 9,034,825
App. No.
14/186,331
Granted
May 19, 2015
Kind
B2
Abstract

Provided are methods of using humanin and humanin analogs to treat a mammal exhibiting or at risk for insulin resistance, increase insulin sensitivity in a mammal exhibiting or at risk for insulin resistance, treat type-2 diabetes mellitus, metabolic syndrome, and neurodegeneration, treat and prevent myocardial injury, and determine longevity.

Claims (2)

1. A method of decreasing myocardial injury in a subject following myocardial ischemia and reperfusion comprising administering to the subject a humanin analog having the amino acid sequence of SEQ ID NO: 4 in an amount effective to reduce myocardial infarct.

2. The method of claim 1 , wherein the subject is a human.

Assignments (2)
MERGER AND CHANGE OF NAME Recorded Feb 26, 2019
From: ALBERT EINSTEIN COLLEGE OF MEDICINE, INC.; ALBERT EINSTEIN COLLEGE OF MEDICINE
To: ALBERT EINSTEIN COLLEGE OF MEDICINE
Reel/Frame 048438/0275 →
CONFIRMATORY LICENSE Recorded Jun 22, 2015
From: ALBERT EINSTEIN COLLEGE OF MEDICINE
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 035984/0346 →