Milk yield and/or milk quality improving agent, perinatal disease preventive or therapeutic agent, and reproductivity improving agent for ruminant
An object of the present invention is to improve the milk yield and/or milk quality of a ruminant for milk production, to prevent or treat a perinatal disease of a ruminant, and to improve the reproductivity of a ruminant. In order to solve the above-mentioned problem, the following is provided. An agent for improving at least one of milk yield and milk quality of a ruminant, comprising at least one of cashew nut shell liquid, heat-treated cashew nut shell liquid, anacardic acid, cardanol, and cardol. An agent for preventing or treating a perinatal disease of a ruminant, comprising at least one of cashew nut shell liquid, heat-treated cashew nut shell liquid, anacardic acid, cardanol, and cardol. An agent for improving reproductivity of a ruminant, comprising at least one of cashew nut shell liquid, heat-treated cashew nut shell liquid, anacardic acid, cardanol, and cardol.
1. A method of treating a perinatal disease in a ruminant in need thereof, comprising:
administering to said ruminant a therapeutically effective amount of a heat-treated cashew nut shell liquid to treat the perinatal disease in said ruminant,
wherein the perinatal disease is selected from the group consisting of hypocalcemia, fatty liver, ketosis, abomasal displacement and combinations thereof, and
wherein the heat treated cashew nut shell liquid is heated to a temperature of 130° C. or higher which significantly changes the amount of anacardic acid, cardanol, and cardol in the cashew nut shell liquid.
2. The method of claim 1 , wherein the heat-treated cashew nut shell liquid is administered to the ruminant in an amount of from 1 to 100 g per ruminant per day.
3. The method of claim 1 , comprising administering the heat-treated cashew nut shell liquid to the ruminant together with at least one oil absorbent selected from the group consisting of magnesium oxide, stearate, talc, zeolite, diatom earth and silica in a mass ratio of 100:20 to 100:180.
4. The method of claim 1 , wherein the ruminant is a periparturient cow.
5. The method of claim 1 , comprising administering the heat-treated cashew nut shell liquid to the ruminant together with a feed, wherein the feed of the method is in a ratio by weight of a forage to the total weight of the forage and a concentrate feed of 0.3 to 1.0.
6. The method of claim 1 , wherein the heat treated cashew nut shell liquid comprises 0-10 mass % anacardic acid, 55-80 mass % cardanol, and 5-30 mass % cardol.
7. The method of claim 1 , wherein the heat treated cashew nut shell liquid comprises 71.4-80 mass % cardanol, and 14.4-30 mass % cardol.