Oligosaccharide conjugates for targeting bacteria and uses related thereto
This disclosure relates to conjugates for targeting bacteria and related uses. In certain embodiments, the disclosure relates to methods of transferring a molecule of interest into bacteria comprising mixing bacteria with a non-naturally occurring conjugate under conditions such that the conjugate is transported across the bacterial cell wall. Typically, the conjugate comprises an oligosaccharide and a molecule of interest. In certain embodiments, the molecule of interest may be a tracer or an antibiotic.
1. A composition comprising a positron-emitting radionuclide conjugated to maltodextrin.
2. The composition of claim 1 , wherein the positron-emitting radionuclide is selected from carbon-11, nitrogen-13, oxygen-15, fluorine-18, rubidium-82, and strontium-82.
3. The composition of claim 1 , wherein the maltodextrin has greater than 2 glucose oligomers.
4. The composition of claim 1 , wherein the composition is